Non-Hodgkin lymphoma mortality disparities across different sexes, races, and geographic locations.

IF 2.5 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL
Journal of Investigative Medicine Pub Date : 2024-10-01 Epub Date: 2024-07-24 DOI:10.1177/10815589241262003
Jia Yi Tan, Yong Hao Yeo, Aharnish Patel, Kok Hoe Chan, Mohammad Muhsin Chisti, Daniel E Ezekwudo
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引用次数: 0

Abstract

Non-Hodgkin lymphoma (NHL) is one of the most common hematological cancers in the United States. The mortality rate of NHL in the United States is the sixth highest among all cancers. Our cross-sectional study aims to examine the trends and disparity in NHL mortality. We analyzed death certificate data from the Centers for Disease Control and Prevention's Wide-Ranging Online Data for Epidemiologic Research (CDC WONDER) United States to determine the NHL mortality trends among the U.S. population aged ≥15 years. NHL (ICD-10 C82-85) was listed as the underlying cause of death. Age-adjusted mortality rates (AAMRs) per 100,000 individuals and joinpoint trend analysis were performed to determine the average annual percent change (AAPC) in AAMR trends. From 1999 to 2020, NHL accounted for 457,143 deaths in the United States, of which 54% are men and 46% are women. The NHL AAMR decreased significantly from 10.59 to 6.21 per 100,000 individuals with an AAPC of -2.55. Men had a higher AAMR than women (10.10 vs 6.29 per 100,000 individuals). Whites recorded the highest AAMR (8.43 per 100,000 individuals), followed by Hispanics (6.32 per 100,000 individuals), Blacks (5.71 per 100,000 individuals), American Indians (5.31 per 100,000 individuals), and Asians (5.10 per 100,000 individuals). Those who lived in the Midwest and the rural areas had the highest AAMR at 8.60 and 8.35 per 100,000 individuals respectively. Despite the declining NHL mortality rate, this study calls for targeted intervention to improve outcomes for susceptible individuals affected by NHL.

快讯:不同性别、种族和地理位置的非霍奇金淋巴瘤死亡率差异。
非霍奇金淋巴瘤(NHL)是美国常见的血液肿瘤之一。在美国,非霍奇金淋巴瘤的死亡率在所有癌症中排名第六。我们的研究旨在探讨 NHL 死亡率的趋势和差异。我们分析了美国疾病控制和预防中心的广泛流行病学研究在线数据(CDC WONDER)中的死亡证明数据,以确定美国年龄≥15 岁人群的 NHL 死亡率趋势。NHL(ICD-10 C82-85)被列为基本死因。通过每 10 万人的年龄调整死亡率(AAMR)和连接点趋势分析,确定了年龄调整死亡率趋势的年均百分比变化(AAPC)。从 1999 年到 2020 年,美国有 457,143 人死于 NHL,其中 54% 为男性,46% 为女性。每 10 万人中,NHL 的 AAMR 从 10.59 显著降至 6.21,AAPC 为-2.55。男性的 AAMR 比女性高(每 10 万人中有 10.10 人,女性为 6.29 人)。白人的 AAMR 最高(每 100,000 人中有 8.43 人),其次是黑人(每 100,000 人中有 5.71 人)、西班牙裔(每 100,000 人中有 6.32 人)、美洲印第安人(每 100,000 人中有 5.31 人)和亚洲人(每 100,000 人中有 5.10 人)。居住在中西部和农村地区的人的AAMR最高,分别为每10万人8.60人和8.35人。尽管 NHL 死亡率在下降,但这项研究呼吁采取有针对性的干预措施,以改善易受 NHL 影响的人群的预后。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of Investigative Medicine
Journal of Investigative Medicine 医学-医学:内科
CiteScore
4.90
自引率
0.00%
发文量
111
审稿时长
24 months
期刊介绍: Journal of Investigative Medicine (JIM) is the official publication of the American Federation for Medical Research. The journal is peer-reviewed and publishes high-quality original articles and reviews in the areas of basic, clinical, and translational medical research. JIM publishes on all topics and specialty areas that are critical to the conduct of the entire spectrum of biomedical research: from the translation of clinical observations at the bedside, to basic and animal research to clinical research and the implementation of innovative medical care.
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