Fructosamine and HbA1c: A Correlational Study in a Southeast Asian Population.

IF 0.6 Q4 ENDOCRINOLOGY & METABOLISM

Journal of the ASEAN Federation of Endocrine Societies Pub Date : 2024-01-01 Epub Date: 2024-02-08 DOI:10.15605/jafes.039.01.14

Kurumbian Chandran, See Muah Lee, Liang Shen, Eng Loon Tng

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引用次数: 0

Abstract

Objectives: Fructosamine correlates well with glycated haemoglobin (HbA1c) in Caucasians. This study investigates this correlation and whether fructosamine can reliably estimate glycated haemoglobin in Southeast Asians.

Methods: We recruited 193 participants based on 4 HbA1c bands (<6.0%; 6.0 - 7.9%; 8.0- 9.9%; ≥10%) from a secondary hospital in Singapore between August 2017 and December 2021. Blood samples for fructosamine, glycated haemoglobin, albumin, haemoglobin, thyroid stimulating hormone and creatinine were drawn in a single setting for all participants. Scatter plot was used to explore correlation between fructosamine and glycated haemoglobin. Strength of linear correlation was reported using Pearson's correlation coefficient. Simple linear regression was used to examine the relationship between fructosamine and glycated haemoglobin.

Results: We performed simple linear regression to study the relationship between fructosamine and HbA1c in the research participants (R² = 0.756, p<0.01). Further analysis with natural logarithmic transformation of fructosamine demonstrated a stronger correlation between HbA1c and fructosamine (R² = 0.792, p<0.01).

Conclusions: Fructosamine is reliably correlated with HbA1c for the monitoring of glycaemic control in Southeast Asians.

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果糖胺与 HbA1c：一项针对东南亚人群的相关研究。

目的：在白种人中，果糖胺与糖化血红蛋白（HbA1c）有很好的相关性。本研究调查了这一相关性，以及果糖胺是否能可靠地估计东南亚人的糖化血红蛋白：方法：我们根据 4 个 HbA1c 波段招募了 193 名参与者（结果见表 2）：我们对研究参与者的果糖胺和 HbA1c 之间的关系进行了简单的线性回归研究（R2 = 0.756，p2 = 0.792，pConclusions：果糖胺与 HbA1c 具有可靠的相关性，可用于监测东南亚人的血糖控制情况。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of the ASEAN Federation of Endocrine Societies ENDOCRINOLOGY & METABOLISM-

CiteScore

1.20

自引率

0.00%

发文量

审稿时长

8 weeks

期刊介绍： The Journal of the ASEAN Federation of Endocrine Societies (JAFES) is an OPEN ACCESS, internationally peer-reviewed, English language, medical and health science journal that is published in print two times a year by the ASEAN Federation of Endocrine Societies. It shall serve as the endocrine window between the ASEAN region and the world, featuring original papers and publishing key findings from specialists and experts of endocrinology.