Synergistic interaction between pay-it-forward incentives and recreational drug use on hepatitis B virus and hepatitis C virus testing among men who have sex with men in China.

IF 3.6 3区医学 Q2 INFECTIOUS DISEASES

Sexually Transmitted Infections Pub Date : 2024-07-26 DOI:10.1136/sextrans-2024-056150

Wei Ai, Yewei Xie, Haidong Lu, Ting Ai, Dan Wu, Ye Zhang, Gifty Marley, Jason Ong, Joseph D Tucker, Weiming Tang

{"title":"Synergistic interaction between pay-it-forward incentives and recreational drug use on hepatitis B virus and hepatitis C virus testing among men who have sex with men in China.","authors":"Wei Ai, Yewei Xie, Haidong Lu, Ting Ai, Dan Wu, Ye Zhang, Gifty Marley, Jason Ong, Joseph D Tucker, Weiming Tang","doi":"10.1136/sextrans-2024-056150","DOIUrl":null,"url":null,"abstract":"Objectives: Pay-it-forward incentives effectively promote hepatitis B virus (HBV) and hepatitis C virus (HCV) testing among men who have sex with men (MSM) by offering free testing and donation opportunities. This study aims to explore the interaction between pay-it-forward incentives and recreational drug use on HBV and HCV testing uptake among Chinese MSM.Methods: We pooled data from two pay-it-forward studies that aimed to promote dual HBV and HCV testing among MSM in Jiangsu, China. We explored factors associated with hepatitis testing uptake in the two study groups and examined the interaction between pay-it-forward incentives and recreational drug use on hepatitis testing uptake.Results: Overall, 511 MSM participated in these two studies, with 265 participants in the pay-it-forward incentives group and 246 participants in the standard-of-care group. Among these participants, 59.3% in the pay-it-forward incentive group and 24.8% in the standard-of-care group received dual HBV and HCV testing, respectively. In the pay-it-forward incentives group, participants who used recreational drugs in the past 12 months (adjusted OR (AOR)=1.83, 95% CI 1.09 to 3.06) were more likely to receive dual HBV and HCV testing, compared with those who never used recreational drugs, whereas in the standard-of-care group, those who used recreational drugs were less likely to receive dual HBC and HCV testing (AOR=0.38, 95% CI 0.18 to 0.78). MSM with higher community connectedness (AOR=1.10, 95% CI 1.00 to 1.21) were also more likely to receive hepatitis testing with pay-it-forward incentives. There was a synergistic interaction on both the multiplicative (ratio of ORs=4.83, 95% CI 1.98 to 11.7) and additive scales (the relative excess risk of interaction=2.97, 95% CI 0.56 to 5.38) of pay-it-forward incentives and recreational drug use behaviours on dual HBV and HCV testing uptake among MSM.Conclusion: Pay-it-forward incentives may be particularly useful in promoting hepatitis testing among MSM who use recreational drugs.","PeriodicalId":21624,"journal":{"name":"Sexually Transmitted Infections","volume":null,"pages":null},"PeriodicalIF":3.6000,"publicationDate":"2024-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11283352/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Sexually Transmitted Infections","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1136/sextrans-2024-056150","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"INFECTIOUS DISEASES","Score":null,"Total":0}

引用次数: 0

Abstract

Objectives: Pay-it-forward incentives effectively promote hepatitis B virus (HBV) and hepatitis C virus (HCV) testing among men who have sex with men (MSM) by offering free testing and donation opportunities. This study aims to explore the interaction between pay-it-forward incentives and recreational drug use on HBV and HCV testing uptake among Chinese MSM.

Methods: We pooled data from two pay-it-forward studies that aimed to promote dual HBV and HCV testing among MSM in Jiangsu, China. We explored factors associated with hepatitis testing uptake in the two study groups and examined the interaction between pay-it-forward incentives and recreational drug use on hepatitis testing uptake.

Results: Overall, 511 MSM participated in these two studies, with 265 participants in the pay-it-forward incentives group and 246 participants in the standard-of-care group. Among these participants, 59.3% in the pay-it-forward incentive group and 24.8% in the standard-of-care group received dual HBV and HCV testing, respectively. In the pay-it-forward incentives group, participants who used recreational drugs in the past 12 months (adjusted OR (AOR)=1.83, 95% CI 1.09 to 3.06) were more likely to receive dual HBV and HCV testing, compared with those who never used recreational drugs, whereas in the standard-of-care group, those who used recreational drugs were less likely to receive dual HBC and HCV testing (AOR=0.38, 95% CI 0.18 to 0.78). MSM with higher community connectedness (AOR=1.10, 95% CI 1.00 to 1.21) were also more likely to receive hepatitis testing with pay-it-forward incentives. There was a synergistic interaction on both the multiplicative (ratio of ORs=4.83, 95% CI 1.98 to 11.7) and additive scales (the relative excess risk of interaction=2.97, 95% CI 0.56 to 5.38) of pay-it-forward incentives and recreational drug use behaviours on dual HBV and HCV testing uptake among MSM.

Conclusion: Pay-it-forward incentives may be particularly useful in promoting hepatitis testing among MSM who use recreational drugs.

查看原文本刊更多论文

中国男男性行为者乙肝病毒和丙肝病毒检测中的 "以奖代补 "激励机制与娱乐性毒品使用之间的协同互动。

目标：以奖代补激励机制通过提供免费检测和捐赠机会，可有效促进男男性行为者（MSM）接受乙肝病毒（HBV）和丙肝病毒（HCV）检测。本研究旨在探讨中国男男性行为者中，以奖代补激励机制和娱乐性吸毒对HBV和HCV检测率的影响：我们汇集了来自两项有偿研究的数据，这两项研究的目的是在中国江苏的 MSM 中推广 HBV 和 HCV 双重检测。我们探讨了这两项研究中与肝炎检测率相关的因素，并研究了 "以奖代补 "激励机制和娱乐性吸毒对肝炎检测率的交互作用：共有511名男男性行为者参加了这两项研究，其中265人参加了 "按劳取酬 "激励机制组，246人参加了 "标准护理 "组。在这些参与者中，有偿激励组和标准护理组分别有 59.3% 和 24.8% 的人接受了 HBV 和 HCV 双重检测。与从未使用过娱乐性毒品的参与者相比，在有偿奖励组中，在过去12个月中使用过娱乐性毒品的参与者（调整OR（AOR）=1.83，95% CI 1.09至3.06）更有可能接受HBV和HCV双重检测，而在标准护理组中，使用过娱乐性毒品的参与者接受HBV和HCV双重检测的可能性较低（AOR=0.38，95% CI 0.18至0.78）。社区关联度较高的 MSM（AOR=1.10，95% CI 1.00 至 1.21）也更有可能接受有偿奖励的肝炎检测。在乘法量表（ORs 比率=4.83，95% CI 1.98 至 11.7）和加法量表（交互作用的相对超额风险=2.97，95% CI 0.56 至 5.38）上，有偿激励和娱乐性吸毒行为对 MSM 接受 HBV 和 HCV 双重检测都有协同交互作用：结论：以奖代补激励措施可能对促进使用娱乐性毒品的 MSM 接受肝炎检测特别有用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Sexually Transmitted Infections 医学-传染病学

CiteScore

5.70

自引率

8.30%

发文量

审稿时长

4-8 weeks

期刊介绍： Sexually Transmitted Infections is the world’s longest running international journal on sexual health. It aims to keep practitioners, trainees and researchers up to date in the prevention, diagnosis and treatment of all STIs and HIV. The journal publishes original research, descriptive epidemiology, evidence-based reviews and comment on the clinical, public health, sociological and laboratory aspects of sexual health from around the world. We also publish educational articles, letters and other material of interest to readers, along with podcasts and other online material. STI provides a high quality editorial service from submission to publication.