Anastomosing hemangioma of the liver in infant: A case report

IF 0.2 Q4 PEDIATRICS
Konstantin Semash , Timur Dzhanbekov , Murat Abduazizov , Sukhrob Tashmatov
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Abstract

Introduction

Anastomosing hemangiomas represent a rare variant of benign vascular hemangioma which rarely arise from the liver parenchyma. The peculiarity of these tumors is that they can mimic malignant tumors, such as hepatocellular carcinoma, hepatoblastoma, and angiosarcoma. Notably, all documented cases where this type of liver tumor was described in the world's literature exclude cases involving infant patients.

Case presentation

Our clinical case demonstrates the presence of an anastomosing hemangioma in the right lobe of the liver in a 5-month-old child, necessitating radical surgical intervention. According to ultrasound and CT scan findings, a tumor measuring 7.5 by 6 by 4.5 cm was detected in the segments V, VII and VIII of the liver. A differential diagnosis between hepatoblastoma and angiosarcoma was conducted. Blood tests, including alpha-fetoprotein levels, were within normal limits. Percutaneous biopsy revealed no cellular atypia, while immunohistochemical examination identified anastomosing hemangioma positive for CD-31 and CD-34 staining. Given the size of the tumor, an anatomical right hepatectomy was performed. The patient was discharged on the 7th postoperative day without surgical complications. After 6 months, no recurrence of the tumor was detected.

Conclusion

This particular case highlights the importance of differential diagnosis of this type of tumor in children since anastomosing hemangiomas can mimic malignant liver tumors.

婴儿肝脏吻合血管瘤:病例报告
导言吻合血管瘤是良性血管瘤的一种罕见变体,很少发生于肝实质。这类肿瘤的特殊性在于它们可以模仿恶性肿瘤,如肝细胞癌、肝母细胞瘤和血管肉瘤。我们的临床病例显示,一名 5 个月大的儿童肝脏右叶出现了吻合血管瘤,必须进行根治性手术治疗。根据超声波和 CT 扫描结果,在肝脏 V、VII 和 VIII 节段发现了一个 7.5 x 6 x 4.5 厘米的肿瘤。对肝母细胞瘤和血管肉瘤进行了鉴别诊断。包括甲胎蛋白水平在内的血液检查均在正常范围内。经皮活检未发现细胞不典型性,免疫组化检查发现吻合血管瘤的CD-31和CD-34染色阳性。考虑到肿瘤的大小,患者接受了解剖性右肝切除术。患者于术后第 7 天出院,未出现手术并发症。6个月后,未发现肿瘤复发。结论:由于吻合血管瘤可与恶性肝肿瘤相仿,因此这一特殊病例凸显了儿童鉴别诊断此类肿瘤的重要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
0.60
自引率
25.00%
发文量
348
审稿时长
15 days
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