Association between asthma and periodontitis: A case-control analysis of risk factors, related medications, and allergic responses.

IF 3.4 3区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE
Muhammad H A Saleh, Ann M Decker, Khushboo Kalani, Khoa Hoang, Obada Mandil, Parth Gathalia, Bidisha Ray, Njira Lugogo, Hom-Lay Wang
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引用次数: 0

Abstract

Aims: This study aimed to investigate the association between asthma, related allergies and medication use, and the presence and severity of periodontitis among individuals at the University of Michigan School of Dentistry.

Methods: Employing a case-control design, the study analyzed data from 892 patients, half with asthma and half without asthma. Data collection included demographics, asthma history, medication use, allergies, and periodontal examination outcomes, including probing pocket depth (PPD), mobility, furcation involvement, and radiographic bone loss (RBL). Logistic regression models assessed the relationship between asthma and periodontitis, adjusting for confounders.

Results: Asthmatic patients exhibited significantly lower odds of periodontitis (OR = 0.10, p < .001) and were less likely to present with advanced stages (OR = 0.23, p < .001) and grades of the disease (OR = 0.31, p < .001) compared to non-asthmatic patients. The study also found a higher proportion of females in the asthmatic group (67% vs. 51.8%, p < .001). Smoking was identified as a significant factor associated with periodontitis in patients with asthma, with former smokers at more than double the odds (OR = 2.28, p = .035) and current smokers at a slightly lower yet significant odds (OR = 1.87, p = .050). Additionally, asthmatic patients on adrenergic inhalers had an increased likelihood of developing periodontitis (OR = 1.76, p = .045). Allergies to codeine and latex were associated with higher odds of periodontitis, with ORs of 3.41 and 6.09, respectively.

Conclusions: Asthma was found to be associated with lower odds of periodontitis. However, this association appears to be modified by smoking habits and the use of certain asthma medications, which are related to an increased likelihood of periodontitis among asthmatic patients.

哮喘与牙周炎之间的关系:对风险因素、相关药物和过敏反应的病例对照分析。
目的:本研究旨在调查密歇根大学牙科学院的哮喘、相关过敏症和药物使用与牙周炎的存在和严重程度之间的关系:研究采用病例对照设计,分析了 892 名患者的数据,其中一半患有哮喘,一半没有哮喘。收集的数据包括人口统计学特征、哮喘病史、用药情况、过敏史和牙周检查结果,包括探诊袋深度(PPD)、活动度、毛囊受累情况和放射骨质流失(RBL)。逻辑回归模型评估了哮喘与牙周炎之间的关系,并对混杂因素进行了调整:结果:哮喘病人患牙周炎的几率明显较低(OR = 0.10,p 结论:哮喘与牙周炎的关系与哮喘病人的哮喘程度有关:哮喘与牙周炎发生几率较低有关。然而,吸烟习惯和使用某些哮喘药物似乎会改变这种关联,因为这与哮喘患者患牙周炎的可能性增加有关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of periodontal research
Journal of periodontal research 医学-牙科与口腔外科
CiteScore
6.90
自引率
5.70%
发文量
103
审稿时长
6-12 weeks
期刊介绍: The Journal of Periodontal Research is an international research periodical the purpose of which is to publish original clinical and basic investigations and review articles concerned with every aspect of periodontology and related sciences. Brief communications (1-3 journal pages) are also accepted and a special effort is made to ensure their rapid publication. Reports of scientific meetings in periodontology and related fields are also published. One volume of six issues is published annually.
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