MRI features of ovarian teratomas with somatic-type malignancy and mature cystic teratomas

IF 2.3 3区医学 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Abdominal Radiology Pub Date : 2024-06-10 DOI:10.1007/s00261-024-04287-8

Takahiko Nakazono, Yutaka Yoshinaga, Ken Yamaguchi, Masatoshi Yokoyama, Keita Kai, Shuichi Fukui, Ryoko Egashira, Kanto Ichinohe, Shigeru Nagaoka, Hiroyuki Irie

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Abstract

Purpose

We evaluated the magnetic resonance imaging (MRI) features of ovarian teratomas with somatic-type malignancy (TSMs) and benign ovarian mature cystic teratomas (MCTs) to determine the diagnostic contribution of the MRI findings for differentiating these two teratomas.

Methods

We compared the MRI findings between ovarian TSMs (n = 10) and MCTs (n = 193), and we conducted a receiver operating characteristic (ROC) analysis to determine the MRI findings' contribution to the differentiation of TSMs from MCTs.

Results

The maximum diameters of whole lesion and the largest solid component in the TSMs were larger than those of the MCTs (p = 0.0001 and p < 0.0001, respectively). Fat tissue in solid components was seen in 73/116 (62.9%) MCTs but in none of the TSMs (p = 0.0001). Ring-like enhancement in solid components was seen in 60/116 (51.7%) MCTs and none of the TSMs (p = 0.0031). On dynamic contrast-enhanced MRI (DCE MRI), all of the solid components in the TSMs showed a high- or intermediate-risk time intensity curve (TIC), and those in 113 of the 116 (97.4%) MCTs showed a low-risk TIC (p < 0.0001). The area under the curve of the ROC analysis using the high-/intermediate-risk TIC on DCE MRI was the highest (0.99) for differentiating TSMs from MCTs: sensitivity 100%, specificity 97.4%, positive predictive value 75.0%, negative predictive value 100%, and accuracy, 97.6%.

Conclusion

Compared to ovarian MCTs, ovarian TSMs are larger and have larger solid components with high- or intermediate-risk TICs on DCE MRI. Ovarian MCTs frequently show small solid components with fat tissue, ring-like enhancement, and a low-risk TIC on DCE MRI.

Graphical abstract

Abstract Image

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卵巢畸胎瘤伴体细胞型恶性肿瘤和成熟囊性畸胎瘤的磁共振成像特征。

目的：我们评估了卵巢体细胞型恶性畸胎瘤（TSMs）和良性卵巢成熟囊性畸胎瘤（MCTs）的磁共振成像（MRI）特征，以确定磁共振成像结果对区分这两种畸胎瘤的诊断贡献：我们比较了卵巢TSMs（n = 10）和MCTs（n = 193）的核磁共振成像结果，并进行了接收者操作特征（ROC）分析，以确定核磁共振成像结果对TSMs和MCTs鉴别的贡献：结果：TSMs的整个病灶和最大实性成分的最大直径均大于MCTs（p = 0.0001和p 结论：与卵巢MCTs相比，TSMs的最大实性成分的直径大于MCTs（p = 0.0001）：与卵巢MCTs相比，卵巢TSMs在DCE MRI上的体积更大，实性成分也更大，且具有高危或中危TICs。卵巢MCT在DCE磁共振成像上经常显示出带有脂肪组织的小实性成分、环状强化和低风险TIC。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Abdominal Radiology Medicine-Radiology, Nuclear Medicine and Imaging

CiteScore

5.20

自引率

8.30%

发文量

334

期刊介绍： Abdominal Radiology seeks to meet the professional needs of the abdominal radiologist by publishing clinically pertinent original, review and practice related articles on the gastrointestinal and genitourinary tracts and abdominal interventional and radiologic procedures. Case reports are generally not accepted unless they are the first report of a new disease or condition, or part of a special solicited section. Reasons to Publish Your Article in Abdominal Radiology: · Official journal of the Society of Abdominal Radiology (SAR) · Published in Cooperation with: European Society of Gastrointestinal and Abdominal Radiology (ESGAR) European Society of Urogenital Radiology (ESUR) Asian Society of Abdominal Radiology (ASAR) · Efficient handling and Expeditious review · Author feedback is provided in a mentoring style · Global readership · Readers can earn CME credits