Correlation between initial serum 25-hydroxyvitamin D and granulation growth in diabetic foot ulcers.

IF 1.5 4区医学 Q3 DERMATOLOGY

Journal of wound care Pub Date : 2024-06-01 DOI:10.12968/jowc.2021.0243

Em Yunir, Fajar Englando Alan Adesta, Aulia Rizka, Tri Juli Edi Tarigan

引用次数: 0

Abstract

Objective: To determine the correlation between initial serum 25-hydroxyvitamin D (25(OH)D) levels with granulation growth in diabetic foot ulcers (DFUs) after 21 days of treatment.

Method: This cohort study involved patients with type 2 diabetes who had a DFU treated at hospital. Blood samples were taken from patients on admission. The chemiluminescent immunoassay technique was used to measure 25(OH)D levels. Granulation tissue growth was analysed by comparing the photographs from the initial treatment to day 21 of treatment.

Results: The median value of 25(OH)D levels at initial treatment was 8 ng/ml. The result showed no correlation between 25(OH)D levels and the granulation growth in DFUs (p=0.86).

Conclusion: The initial serum 25(OH)D level was not correlated with the growth of granulation tissue in DFUs.

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糖尿病足溃疡中初始血清 25- 羟维生素 D 与肉芽生长之间的相关性。

目的确定初始血清 25- 羟维生素 D (25(OH)D) 水平与治疗 21 天后糖尿病足溃疡（DFU）肉芽生长之间的相关性：这项队列研究涉及在医院接受治疗的 2 型糖尿病足溃疡患者。患者在入院时抽取血液样本。采用化学发光免疫测定技术测量 25(OH)D 水平。通过比较从最初治疗到治疗第 21 天的照片，分析肉芽组织的生长情况：结果：初始治疗时 25（OH）D 水平的中位值为 8 纳克/毫升。结果显示，25（OH）D 水平与 DFU 的肉芽生长无相关性（P=0.86）：结论：初始血清 25（OH）D 水平与 DFU 肉芽组织的生长无关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of wound care DERMATOLOGY-

CiteScore

2.90

自引率

10.50%

发文量

215

期刊介绍： Journal of Wound Care (JWC) is the definitive wound-care journal and the leading source of up-to-date research and clinical information on everything related to tissue viability. The journal was first launched in 1992 and aimed at catering to the needs of the multidisciplinary team. Published monthly, the journal’s international audience includes nurses, doctors and researchers specialising in wound management and tissue viability, as well as generalists wishing to enhance their practice. In addition to cutting edge and state-of-the-art research and practice articles, JWC also covers topics related to wound-care management, education and novel therapies, as well as JWC cases supplements, a supplement dedicated solely to case reports and case series in wound care. All articles are rigorously peer-reviewed by a panel of international experts, comprised of clinicians, nurses and researchers. Specifically, JWC publishes: High quality evidence on all aspects of wound care, including leg ulcers, pressure ulcers, the diabetic foot, burns, surgical wounds, wound infection and more The latest developments and innovations in wound care through both preclinical and preliminary clinical trials of potential new treatments worldwide In-depth prospective studies of new treatment applications, as well as high-level research evidence on existing treatments Clinical case studies providing information on how to deal with complex wounds Comprehensive literature reviews on current concepts and practice, including cost-effectiveness Updates on the activities of wound care societies around the world.