Adjunctive hyperbaric oxygen treatment for challenging pyoderma gangrenosum cases

Abstract

Introduction

Pyoderma gangrenosum (PG) is a rare, difficult-to-treat neutrophilic ulcerative cutaneous condition that severely impacts those affected. Treatment options for PG are limited, and disease remission is not guaranteed. Hyperbaric oxygen treatment is a potential therapeutic option for treating various ulcerative conditions not frequently utilized for PG.

Case report

We present a case of a patient with treatment-resistant PG who achieved remission with adjunctive HBOT, and then later had difficulty achieving remission without HBOT during a future flare.

Discussion

HBOT should be more readily considered as a treatment option for those with PG.