Oxidation Study of Oleocanthal and Oleacein Induced by Oxone.

IF 2.1 4区医学 Q3 CHEMISTRY, MEDICINAL

Planta medica Pub Date : 2024-06-01 Epub Date: 2024-06-06 DOI:10.1055/a-2235-0009

Lemonia Antoniadi, Apostolis Angelis, Ioannis K Kostakis, Leandros A Skaltsounis

引用次数: 0

Abstract

A selective Oxone-induced oxidation of oleocanthal and oleacein, the two main secoiridoids of olive oil, to their bis-oxidized products is described. This protocol is based on a Baeyer-Villiger mechanism and the concentration of Oxone in the final solution. The bis-oxidation of the aldehydic compounds could be extended for the synthesis of various semisynthetic analogs. The obtained acids exhibit strong antioxidant activity, being efficient free radical scavengers.

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氧化酮诱导的油菜醛和油菜素氧化研究

本文介绍了一种由 Oxone 诱导的选择性氧化方法，可将橄榄油中的两种主要仲呋喃类物质--油菜醛和油菜素氧化为其双氧化产物。该方案基于 Baeyer-Villiger 机制和最终溶液中 Oxone 的浓度。醛类化合物的双氧化反应可用于合成各种半合成类似物。所得到的酸具有很强的抗氧化活性，是高效的自由基清除剂。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Planta medica 医学-药学

CiteScore

5.10

自引率

3.70%

发文量

101

审稿时长

1.8 months

期刊介绍： Planta Medica is one of the leading international journals in the field of natural products – including marine organisms, fungi as well as micro-organisms – and medicinal plants. Planta Medica accepts original research papers, reviews, minireviews and perspectives from researchers worldwide. The journal publishes 18 issues per year. The following areas of medicinal plants and natural product research are covered: -Biological and Pharmacological Activities -Natural Product Chemistry & Analytical Studies -Pharmacokinetic Investigations -Formulation and Delivery Systems of Natural Products. The journal explicitly encourages the submission of chemically characterized extracts.