Heavy Metals Cause Toxicity, Histopathological Abnormalities and Oxidative Stress in Major Carps (Catla catla, Labeo rohita and Cirrhinus mrigala)

Maria Saeed Khan, Abdul Ghaffar, Habiba Jamil, Shumaila Khalid, Batha Tafazul
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Abstract

An aquatic ecosystem is significantly contaminated by the unrestricted release of heavy metals from agricultural and industrial waste. Enhancement of industries correlates with improper dumping of waste products, influencing water pollution via releasing elevated concentrations of heavy metals, including nickel (Ni), chromium (Cr), copper (Cu), silver (Ag), cadmium (Cd), zinc (Zn), and iron (Fe). Metals are the primary motive for causing a variety of anomalies in aquatic animals, including fish. Commercially, humans use freshwater fish as food in various regions of Asia. The excessive release of these metals causes toxicity in fish, which is unsafe for human consumption. Heavy metals cause histological alteration and abnormalities in various fish species, including Indian significant carps (Thala, rohu, mori). Additionally, their toxicity causes oxidative stress in aquatic species. Various techniques have recently been applied to reduce toxic contaminants in marine environments. However, the bioremediation process plays a major role in lowering the toxicants through microorganisms, especially various species of bacteria. The objective of the recent study was to specify the specific organs (liver, gills, kidney, brain, muscle, and heart) of fish that are examined for histopathological impacts. 
重金属导致主要鲤鱼(鲶鱼、鲮鱼和鲫鱼)中毒、组织病理学异常和氧化应激
农业和工业废物无限制地释放重金属,严重污染了水生生态系统。工业的发展与废品的不当倾倒有关,通过释放高浓度的重金属,包括镍(Ni)、铬(Cr)、铜(Cu)、银(Ag)、镉(Cd)、锌(Zn)和铁(Fe),影响水体污染。金属是导致包括鱼类在内的水生动物出现各种异常的主要原因。从商业角度看,亚洲各地区的人类将淡水鱼作为食物。这些金属的过量释放会导致鱼类中毒,对人类食用不安全。重金属会导致各种鱼类,包括印度重要的鲤科鱼类(Thala、rohu、mori)的组织学改变和异常。此外,重金属的毒性还会导致水生物种氧化应激。最近,人们采用了各种技术来减少海洋环境中的有毒污染物。然而,生物修复过程在通过微生物(尤其是各种细菌)降低有毒物质方面发挥着重要作用。近期研究的目的是明确检查鱼类组织病理学影响的特定器官(肝脏、鳃、肾脏、大脑、肌肉和心脏)。
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