Radiation doses and diagnostic reference levels for common CT scans in adults in Northwest region of Iran.

IF 1.5 4区 环境科学与生态学 Q3 BIOLOGY
Radiation and Environmental Biophysics Pub Date : 2024-11-01 Epub Date: 2024-06-05 DOI:10.1007/s00411-024-01074-3
Sina Mardfar, Mona Fazel Ghaziyani, Tohid Mortezazadeh, Hamed Zamani, Melika Rahimiyan, Davood Khezerloo
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Abstract

This study aims to estimate organ dose and cancer risks, establish region-specific diagnostic reference levels (DRLs), and determine achievable doses (ADs) for common CT procedures in adults in the northwest of Iran. Effective and organ doses were estimated using VirtualDoseCT software in a sample of 480 adult patients who underwent head, sinus, chest, and abdomen-pelvis (AP) CT scans. The guidelines provided by the BEIR VII report were utilized to estimate cancer risks. Effective and organ doses for specific procedures were determined, with the highest mean organ dose being observed in the brain during head CT examinations, with a value of 54.02 mGy. It was observed that the lungs in chest examinations and the colon in AP examinations had the highest risk of cancer, with rates of 30.72 and 21.37 per 100,000 persons, respectively. Higher cancer risk values were generally exhibited by females compared to males. The DRLs for common CT examinations were established as follows: Head CT (CTDIvol 41 mGy, DLP 760 mGy cm), Sinus CT (CTDIvol 16 mGy, DLP 261 mGy cm), Chest CT (CTDIvol 8 mGy, DLP 287 mGy cm), and AP CT (CTDIvol 9 mGy, DLP 508 mGy cm). Significant variations in dose distribution among facilities were identified, indicating the need for optimization. The study highlights the importance of minimizing radiation exposure to critical organs and promoting patient safety in CT examinations. The establishment of region-specific DRLs and ADs can help optimize radiation doses and reduce cancer risks for patients.

Abstract Image

伊朗西北部地区成人普通 CT 扫描的辐射剂量和诊断参考水平。
本研究旨在估算器官剂量和癌症风险,建立特定地区的诊断参考水平 (DRL),并确定伊朗西北部成人常见 CT 程序的可达到剂量 (AD)。使用 VirtualDoseCT 软件估算了 480 名接受头部、鼻窦、胸部和腹部-骨盆 (AP) CT 扫描的成年患者的有效剂量和器官剂量。估算癌症风险时采用了 BEIR VII 报告提供的指南。确定了特定程序的有效剂量和器官剂量,观察到头部 CT 检查中大脑的平均器官剂量最高,为 54.02 mGy。据观察,胸部检查中的肺部和 AP 检查中的结肠罹患癌症的风险最高,分别为每 10 万人 30.72 例和 21.37 例。与男性相比,女性患癌症的风险值普遍较高。常见 CT 检查的 DRL 确定如下:头部 CT(CTDIvol 41 mGy,DLP 760 mGy 厘米)、鼻窦 CT(CTDIvol 16 mGy,DLP 261 mGy 厘米)、胸部 CT(CTDIvol 8 mGy,DLP 287 mGy 厘米)和 AP CT(CTDIvol 9 mGy,DLP 508 mGy 厘米)。研究发现,不同设备之间的剂量分布存在显著差异,表明需要进行优化。这项研究强调了在 CT 检查中最大限度减少对重要器官的辐照和促进患者安全的重要性。建立针对特定地区的 DRL 和 AD 可以帮助优化辐射剂量,降低患者的癌症风险。
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来源期刊
CiteScore
4.00
自引率
5.90%
发文量
53
审稿时长
>36 weeks
期刊介绍: This journal is devoted to fundamental and applied issues in radiation research and biophysics. The topics may include: Biophysics of ionizing radiation: radiation physics and chemistry, radiation dosimetry, radiobiology, radioecology, biophysical foundations of medical applications of radiation, and radiation protection. Biological effects of radiation: experimental or theoretical work on molecular or cellular effects; relevance of biological effects for risk assessment; biological effects of medical applications of radiation; relevance of radiation for biosphere and in space; modelling of ecosystems; modelling of transport processes of substances in biotic systems. Risk assessment: epidemiological studies of cancer and non-cancer effects; quantification of risk including exposures to radiation and confounding factors Contributions to these topics may include theoretical-mathematical and experimental material, as well as description of new techniques relevant for the study of these issues. They can range from complex radiobiological phenomena to issues in health physics and environmental protection.
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