Management of refined and personalized newborn blood specimen collection

IF 1.7 Q3 MEDICAL LABORATORY TECHNOLOGY
Hui-Bin Huang , Yu-Bin Lin , Jin-Hua Chen , Min Zhu , Li-Jin Chen , Wang Ye , Lin-Hua Luo , Hui-ming Ye
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引用次数: 0

Abstract

Background

Iatrogenic blood loss is an important cause of neonatal anemia. In this study, a spreadsheet tool was developed to reduce blood collection, providing a new idea for the prevention of iatrogenic blood loss in newborns.

Methods

Based on hematocrit, minimum test volume and dead volume, a new tool was to calculate the minimum blood collection volume and the number of containers required for the test portfolio. We collected data from October 2022 to October 2023 from Xiamen Maternal and Child Health Hospital for analysis and validation.

Results

During this year, there were 16,434 patients and 13,696 plasma/serological samples in the neonatology department. Among them, there were 8 test combinations of greater than 1%, and 9490 samples in total. According to the hospital manual, the recommended amount of blood collection is 27,534 ml and 9490 containers. Through the analysis of this tool, total blood collection was 8864.77 ml, marked qnantity of upward containers (closest level to the calculated blood collection volume) was 10301 ml, and the amount of containers was 8835, which decreased by 67.8%, 62.58% and 6.9% respectively. Besides, if the hematocrit information cannot be obtained in advance and the high hematocrit is calculated as 0.8, the recommended amount of blood collection is 14334.3 ml, and the marked amount of the upward container markering is 17340 ml, decreasing by 47.9% and 37.02% respectively.

Conclusion

We have developed an auxiliary tool that can manage neonatal blood specimen collection in a fine and personalized way and can be applied among different laboratory instruments by parameters modification.

新生儿血液标本采集的精细化和个性化管理
背景先天性失血是新生儿贫血的一个重要原因。本研究开发了一种电子表格工具来减少采血量,为预防新生儿先天性失血提供了新思路。方法根据血细胞比容、最小检测量和死体积,计算最小采血量和检测组合所需的容器数量。我们收集了厦门市妇幼保健院 2022 年 10 月至 2023 年 10 月的数据进行分析和验证。结果这一年,新生儿科共有 16434 名患者和 13696 份血浆/血清样本。其中,大于 1%的检测组合有 8 种,共 9490 份样本。根据医院手册,建议采血量为 27534 毫升,采血容器为 9490 个。通过该工具的分析,总采血量为 8864.77 毫升,标明向上容器的数量(最接近计算采血量的水平)为 10301 毫升,容器数量为 8835 个,分别减少了 67.8%、62.58% 和 6.9%。此外,若无法提前获取血细胞比容信息,计算高血细胞比容为 0.8,则推荐采血量为 14334.3 ml,向上容器标记的标记量为 17340 ml,分别减少了 47.9%和 37.02%。
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来源期刊
Practical Laboratory Medicine
Practical Laboratory Medicine Health Professions-Radiological and Ultrasound Technology
CiteScore
3.50
自引率
0.00%
发文量
40
审稿时长
7 weeks
期刊介绍: Practical Laboratory Medicine is a high-quality, peer-reviewed, international open-access journal publishing original research, new methods and critical evaluations, case reports and short papers in the fields of clinical chemistry and laboratory medicine. The objective of the journal is to provide practical information of immediate relevance to workers in clinical laboratories. The primary scope of the journal covers clinical chemistry, hematology, molecular biology and genetics relevant to laboratory medicine, microbiology, immunology, therapeutic drug monitoring and toxicology, laboratory management and informatics. We welcome papers which describe critical evaluations of biomarkers and their role in the diagnosis and treatment of clinically significant disease, validation of commercial and in-house IVD methods, method comparisons, interference reports, the development of new reagents and reference materials, reference range studies and regulatory compliance reports. Manuscripts describing the development of new methods applicable to laboratory medicine (including point-of-care testing) are particularly encouraged, even if preliminary or small scale.
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