In Vitro Study of Antioxidant and Antimicrobial Activities of Garcinia mangostana L. Peel Extract

Abstract

Plant extract are natural additives that are in great demand. Many biological capabilities of plant extracts in the fields of health and medicine, make research on plant extract quite rapid. Mangosteen (Garcinia mangostana L.) is one of the most famous fruits in Indonesia. In this paper, the antimicrobial and antioxidant activities of mangosteen peel were studied. The mangosteen peel extract were prepared by maceration method using ethanol for 48 hours. After the evaporation, the crude extracts were tested using DPPH assay for antioxidant activity and antibacterial activity was performed using dilution method. The scavenging activity of mangosteen peel extracts values in the range of 73.57 – 79.14% with extract concentration of 100 ppm to 800 ppm, respectively. The antibacterial activity of mangosteen peel extract were conducted against Gram-positive bacteria (S. aureus) and Gram-negative bacteria (E. coli). The inhibition zone of mangosteen peel extract was 6.95 mm against S. aureus and 5.33 ppm against E. coli at extract concentration of 10000 ppm. The results obtained indicate that mangosteen peel extract is potentially applied in the fields of medicine and health.