Maria Isabel Cardona, Melanie Luppa, Andrea Zülke, Eric S Kroeber, Alexander Bauer, Juliane Döhring, Catharina Escales, Christian Brettschneider, Thomas Frese, Robert P Kosilek, Jochen Gensichen, Wolfgang Hoffmann, Hanna Kaduszkiewicz, Hans-Helmut König, Birgitt Wiese, Steffi G Riedel-Heller, Jochen René Thyrian
{"title":"Mediating Factors Associated With Physical Activity in Older Adults at Increased Dementia Risk.","authors":"Maria Isabel Cardona, Melanie Luppa, Andrea Zülke, Eric S Kroeber, Alexander Bauer, Juliane Döhring, Catharina Escales, Christian Brettschneider, Thomas Frese, Robert P Kosilek, Jochen Gensichen, Wolfgang Hoffmann, Hanna Kaduszkiewicz, Hans-Helmut König, Birgitt Wiese, Steffi G Riedel-Heller, Jochen René Thyrian","doi":"10.1177/15333175241257849","DOIUrl":null,"url":null,"abstract":"<p><p>While regular physical-activity (PA) is beneficial, multimorbid individuals at increased dementia risk may exhibit reduced PA levels. Thus, a more comprehensive understanding of mediating factors responsible for inactivity in this population is needed. This study investigated the impact of a multimodal intervention on PA changes at 24-month follow-up and associated mediating factors among community-dwelling patients aged 60-77, with increased dementia risk determined by the CAIDE Dementia Risk Score. Of 1030 participants recruited, 819 completed the assessment. Thus, a generalized estimating equations model initially assessed differences in PA over 24 months, followed by a tree analysis identifying mediating factors influencing PA changes post-intervention. While no significant effect on regular PA was found during the follow-up (<i>P</i> = .674), subgroup analysis revealed improved self-efficacy (<i>P</i> = .000) associated with increased engagement in PA. Incorporating self-efficacy elements into future strategies is crucial for promoting PA among individuals with multimorbidity and at increased dementia risk.</p>","PeriodicalId":93865,"journal":{"name":"American journal of Alzheimer's disease and other dementias","volume":"39 ","pages":"15333175241257849"},"PeriodicalIF":0.0000,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11149443/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"American journal of Alzheimer's disease and other dementias","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1177/15333175241257849","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
While regular physical-activity (PA) is beneficial, multimorbid individuals at increased dementia risk may exhibit reduced PA levels. Thus, a more comprehensive understanding of mediating factors responsible for inactivity in this population is needed. This study investigated the impact of a multimodal intervention on PA changes at 24-month follow-up and associated mediating factors among community-dwelling patients aged 60-77, with increased dementia risk determined by the CAIDE Dementia Risk Score. Of 1030 participants recruited, 819 completed the assessment. Thus, a generalized estimating equations model initially assessed differences in PA over 24 months, followed by a tree analysis identifying mediating factors influencing PA changes post-intervention. While no significant effect on regular PA was found during the follow-up (P = .674), subgroup analysis revealed improved self-efficacy (P = .000) associated with increased engagement in PA. Incorporating self-efficacy elements into future strategies is crucial for promoting PA among individuals with multimorbidity and at increased dementia risk.