Antimicrobial resistance pattern and uropathogens distribution in children visiting a referral hospital in Mogadishu.

IF 2.4 Q3 MEDICINE, RESEARCH & EXPERIMENTAL

Future Science OA Pub Date : 2024-05-15 eCollection Date: 2024-01-01 DOI:10.2144/fsoa-2023-0298

Abdikarin Ahmed Mohamed, Yavuz Bastug, Cem Senol, Mohamed Muktar Kassim, Abdisalam Abdullahi Yusuf, Abdikarim Hussein Mohamed

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Abstract

Aim: Studies concerning epidemiology and drug susceptibility patterns of pediatric urinary tract infection in developing countries are scarce. This study aimed to evaluate the antimicrobial resistance pattern and uropathogens distribution in children. Method: Four-year retrospective study included 840 participants in all pediatric age groups whose urine had been cultured. Results: The prevalence of culture-proven pediatric UTIs was 17.6% (148/840). Escherichia coli was the most common pathogen isolated from the cultures, accounting for (48%, 71/148), followed by Klebsiella pneumoniae (16.2%, 24/148). About 27% of the pathogens had a multidrug-resistant (MDR) pattern. A resistance rate against nitrofurantoin at 24.6%, fosfomycin at 15.2% and trimethoprim-sulfamethoxazole (SMX-TMP) at 79.7% was noted. Conclusion: E. coli and Klebsiella pneumoniae were the most common pathogens isolated.

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摩加迪沙一家转诊医院就诊儿童的抗菌药耐药性模式和尿路病原体分布。

目的：有关发展中国家儿童尿路感染的流行病学和药物敏感性模式的研究很少。本研究旨在评估儿童的抗菌药耐药性模式和尿路病原体分布。研究方法为期四年的回顾性研究纳入了 840 名尿液经过培养的所有儿童年龄组的参与者。研究结果经培养证实的儿科尿路感染发病率为 17.6%（148/840）。大肠埃希菌是从培养物中分离出的最常见病原体，占 48%（71/148），其次是肺炎克雷伯菌（16.2%，24/148）。约 27% 的病原体具有耐多药（MDR）模式。对硝基呋喃妥因的耐药率为 24.6%，对磷霉素的耐药率为 15.2%，对三甲双胍-磺胺甲恶唑（SMX-TMP）的耐药率为 79.7%。结论大肠杆菌和肺炎克雷伯菌是最常见的病原体。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Future Science OA MEDICINE, RESEARCH & EXPERIMENTAL-

CiteScore

5.00

自引率

4.00%

发文量

审稿时长

13 weeks

期刊介绍： Future Science OA is an online, open access, peer-reviewed title from the Future Science Group. The journal covers research and discussion related to advances in biotechnology, medicine and health. The journal embraces the importance of publishing all good-quality research with the potential to further the progress of research in these fields. All original research articles will be considered that are within the journal''s scope, and have been conducted with scientific rigour and research integrity. The journal also features review articles, editorials and perspectives, providing readers with a leading source of commentary and analysis. Submissions of the following article types will be considered: -Research articles -Preliminary communications -Short communications -Methodologies -Trial design articles -Trial results (including early-phase and negative studies) -Reviews -Perspectives -Commentaries