A survey on mean glandular dose in mammography examination and the factors affecting it in Shahid Sadoughi Hospital, Yazd, Iran.

Abstract

Background: mammography is the gold standard in the early detection of breast cancer. Due to the increase in the rate of women suffering from this malignancy all over the world, this imaging modality has been widely used. Considering the side effects caused by ionizing radiation to measure the carcinogenic risk of mammography X-rays, mean glandular dose (MGD) is the best parameter to evaluate the dose received by patients undergoing mammography. The aims of this study were to measure MGD in mammography in mammographic craniocaudal (CC) and mediolateral oblique (MLO) projections and investigate the relationship of MGD with compressed breast thickness (CBT), body mass index, age of the patient, and device exposure conditions.

Materials and methods: this cross-sectional analytical study was conducted on women aged 30-70 referring to the mammography unit of Shahid Sadoughi Hospital in Yazd city from May to August 2022. The TLD-GR 200 (thermoluminescence dosimeter) was placed on the breast of the patients for CC and MLO projections, and then the MGD was obtained by multiplying the entrance surface dose and the normalized glandular dose. Analysis of data (such as demographic information of patients, CBT, kVp, and mAs) was done by SPSS 23 software. The normality of the data was checked using Shapiro-Wilk tests. It was found that except for age, other variables did not have a normal distribution; therefore, equivalent parametric and nonparametric tests were used. In this regard, Spearman's correlation was used to assess the correlation between variables. P-value < .05 was considered as level of significance.

Results: The mean ± standard deviation (SD) age of patients was 47.3 ± 7.1 years. The median ± IQR (the interquartile range (IQR) is a measure of statistical dispersion, which is the spread of the data. It is defined as the difference between the 75th and 25th percentiles of the data.) (mean ± SD) value of MGD per woman was 1.2 ± 0.4 mGy (1.3 ± 0.3 mGy). The median ± IQR MGD in the MLO and CC projections was 1.6 ± 0.6 mGy and 0.9 ± 0.4 mGy, respectively. Significant relationships (P-value ≤ .001) were observed between MGD with CBT (R = 0.62) and age (R = -0.85).

Conclusion: The results showed that the mammography unit at Shahid Sadoughi Hospital in Yazd is functioning properly. The calculated median ± IQR MGD per woman referring to this unit (1.2 ± 0.4 mGy) was clearly below the dose limit recommended by American College of Radiology and International Commission on Radiological Protection (3 mGy). Moreover, among the factors affecting MGD, the highest correlation was seen between MGD and age (R = -0.85).