A nano-molar sensitive fluorescence sensor for cucurbit[7]uril

IF 1.7 4区化学 Q3 CHEMISTRY, MULTIDISCIPLINARY

Journal of Chemical Sciences Pub Date : 2024-05-29 DOI:10.1007/s12039-024-02285-3

Karuppasamy Karpagalakshmi, Ramesh Prakash, Govindaraj Usha, Pavitra Rajendran, Lakshminarayanan Piramuthu, Narayanan Selvapalam

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引用次数: 0

Abstract

Cucurbit[n]urils (CB[n], n = 5–8) are the most important class of host molecules that are widely applied in various important applications. Until now, no sensitive sensor has been developed exclusively for detecting cucurbiturils. Here, we have utilized the supramolecular assembly of acriflavine and graphene oxide (ACF-GO) as a fluorescence sensor for the detection of cucurbituril family members such as CB[5], CB[6] and CB[7] with the discrimination of fluorescence intensities. Among them, CB[7] displayed the highest sensitivity, which can be detected as low as nano-molar concentration, and that allowed us to make a facile fluorescence method of detection for CB[7] and other CBs.

Graphical abstract

Supramolecular assembly of acriflavine on the graphene oxide turn-off the fluorescence of acriflavine and upon interaction with cucurbit[7]uril, that released the acriflavine to the solution and turn-on the fluorescence, which allowed to detect the CB[7] to the lowest of nano-molar concentration.

Abstract Image

查看原文本刊更多论文

一种纳米摩尔灵敏度的葫芦[7]脲荧光传感器

葫芦脲（CB[n]，n = 5-8）是一类最重要的宿主分子，被广泛应用于各种重要领域。迄今为止，尚未开发出专门用于检测葫芦脲的灵敏传感器。在此，我们利用箭毒碱和氧化石墨烯的超分子组装（ACF-GO）作为荧光传感器，通过荧光强度的判别来检测葫芦素家族成员，如 CB[5]、CB[6]和 CB[7]。其中，CB[7]的灵敏度最高，其检测浓度可低至纳摩尔级，这使我们能够对CB[7]和其他CBs进行简便的荧光检测。图解摘要在氧化石墨烯上组装离心黄素的超分子化合物可关闭离心黄素的荧光，当与葫芦[7]脲相互作用时，可将离心黄素释放到溶液中并开启荧光，从而可检测到最低纳米摩尔浓度的 CB[7]。

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来源期刊

Journal of Chemical Sciences CHEMISTRY, MULTIDISCIPLINARY-

CiteScore

3.10

自引率

5.90%

发文量

107

审稿时长

1 months

期刊介绍： Journal of Chemical Sciences is a monthly journal published by the Indian Academy of Sciences. It formed part of the original Proceedings of the Indian Academy of Sciences – Part A, started by the Nobel Laureate Prof C V Raman in 1934, that was split in 1978 into three separate journals. It was renamed as Journal of Chemical Sciences in 2004. The journal publishes original research articles and rapid communications, covering all areas of chemical sciences. A significant feature of the journal is its special issues, brought out from time to time, devoted to conference symposia/proceedings in frontier areas of the subject, held not only in India but also in other countries.