Tumour or haemorrhage?: Differential diagnosis of an unknown mass within the brain of a budgerigar (Melopsittacus undulatus) using a novel imaging pipeline

IF 0.3 Q4 VETERINARY SCIENCES
Tatiana Vasquez, Paul M. Gignac, Peter Brewer, Maria Eugenia Leone Gold
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引用次数: 0

Abstract

We report on a previously healthy zoo specimen of an adult budgerigar (Melopsittacus undulatus, obtained with permission from Southwick's Zoo) found deceased in its enclosure. To assess cause of death and ensure the absence of an infectious neoplasia, we used an integrated multiscale brain‐imaging workflow, previously only used on mammals. The specimen was imaged with microcomputed tomography before and after enhancing soft‐tissue contrast with diffusible iodine‐based contrast‐enhanced microcomputed tomography. Scans revealed an orbital blowout fracture and an unidentified large mass across majority of the diencephalon, striatum and midbrain caudal to the right orbit. After destaining, neural pathohistology confirmed the mass as a brain haemorrhage with no evidence of neoplasia or inflammation. We conclude that this specimen died of head trauma, likely from a head‐on collision within its enclosure. This multiscale imaging workflow (diffusible iodine‐based contrast‐enhanced microcomputed tomography followed by destaining and pathohistology) can improve our evaluation of differential diagnoses in avian specimens.
肿瘤还是出血?使用新型成像管道对虎皮鹦鹉(Melopsittacus undulatus)脑内的不明肿块进行鉴别诊断
我们报告了在动物园发现的一只健康的成年虎皮鹦鹉(Melopsittacus undulatus,经南威克动物园许可获得)标本,该标本在围栏中死亡。为了评估死因并确保不存在传染性肿瘤,我们使用了以前仅用于哺乳动物的综合多尺度脑成像工作流程。在使用可扩散碘对比剂增强微计算机断层扫描增强软组织对比度之前和之后,我们使用微计算机断层扫描对标本进行了成像。扫描结果显示,右侧眼眶后方的大部分双脑、纹状体和中脑存在眼眶爆裂性骨折和不明巨大肿块。去链后,神经病理组织学证实肿块为脑出血,无肿瘤或炎症迹象。我们的结论是,该标本死于头部创伤,很可能是在其围栏内正面碰撞所致。这种多尺度成像工作流程(基于扩散碘的对比度增强微计算机断层扫描,然后进行去染和病理组织学检查)可以改善我们对禽类标本鉴别诊断的评估。
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来源期刊
Veterinary Record Case Reports
Veterinary Record Case Reports Veterinary-Veterinary (all)
CiteScore
0.50
自引率
33.30%
发文量
266
期刊介绍: Vet Record Case Reports is an online resource that publishes articles in all fields of veterinary medicine and surgery so that veterinary professionals, researchers and others can easily find important information on both common and rare conditions. Articles may be about a single animal, herd, flock or other group of animals managed together. Common cases that present a diagnostic, ethical or management challenge, or that highlight aspects of mechanisms of injury, pharmacology or histopathology are deemed of particular educational value. All articles are peer reviewed and copy edited before publication.
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