Tissue changes around dental implants installed in alveolar ridge preservation sites: A 1-year follow-up randomized controlled clinical trial

IF 3.7 2区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Clinical Implant Dentistry and Related Research Pub Date : 2024-05-28 DOI:10.1111/cid.13348

Eran Gabay DMD, PhD, Eli Regev DMD, Yaniv Mayer DMD, Jacob Horwitz DMD, Thabet Asbi DMD, Ofir Ginesin DMD, Hadar Zigdon-Giladi DMD, PhD

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引用次数: 0

Abstract

Objective

This study aimed to assess radiographic marginal bone changes 22 months post extraction, which is 1 year after implant loading in alveolar ridge preservation (ARP) sites grafted with a combination of collagen-embedded xenogenic bone substitute (DBBM-C) and collagen matrix (CMX), comparing them with implants placed in naturally healed sites.

Methods

This randomized controlled clinical trial was conducted over 22 months. Patients who needed a single tooth extraction and subsequent implant placement in nonmolar areas were enrolled. The test group received deproteinized bovine bone mineral with 10% collagen covered by a procaine collagen membrane, while the control group allowed spontaneous healing. Radiographic bone level changes were documented using periapical radiographs at implant placement and follow-up visits (6, 10, and 22 months postextraction). Early implant soft tissue exposure, clinical parameters, and patient-reported outcomes were recorded.

Results

Twenty-two out of 28 participants completed a 22-month follow-up, 9 in the test group and 13 in the control group. At 10-month postextraction follow-up, the mean MBL was 1.01 ± 1.04 mm in the treatment group and 0.81 ± 0.93 mm in the control group (p = 0.804). At 22 months, the mean MBL was 2.09 ± 1.03 mm in the treatment group and 1.58 ± 0.73 mm in the control group (p = 0.339). No statistically significant differences in probing depth (PD) and bleeding on probing (BOP) were found at the 22 -month follow-up as well. Soft tissue mean recession was observed in the control group (0.36 ± 0.84 mm), while no recession was found in the test group (p = 0.2). Early implant soft tissue exposure occurred in 33% of test group participants, while none was observed in the control group (p = 0.047).

Conclusion

One year after implant loading, no significant differences in marginal bone resorption were found between implants placed in ARP-treated and naturally healed sites. However, ARP-treated sites exhibited early implant soft-tissue exposure, suggesting a possible impairment in soft tissue healing.

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牙槽嵴保留区种植体周围组织的变化：为期 1 年的随机对照临床试验。

研究目的本研究旨在评估拔牙后 22 个月，即种植体植入牙槽嵴保留（ARP）部位 1 年后的放射学边缘骨变化，并将其与自然愈合部位的种植体进行比较：这项随机对照临床试验为期 22 个月。方法：这项随机对照临床试验历时 22 个月，研究对象为需要拔除单颗牙齿并随后在非磨牙区植入种植体的患者。试验组接受含有 10%胶原蛋白的去蛋白牛骨矿物质，并覆盖一层普鲁卡因胶原蛋白膜，而对照组则允许自然愈合。在植入种植体和随访（拔牙后 6 个月、10 个月和 22 个月）时，使用根尖周X光片记录骨水平的变化。记录早期种植体软组织暴露情况、临床参数和患者报告结果：28 名参与者中有 22 人完成了 22 个月的随访，其中试验组 9 人，对照组 13 人。在拔牙后 10 个月的随访中，治疗组的平均 MBL 为 1.01 ± 1.04 毫米，对照组为 0.81 ± 0.93 毫米（p = 0.804）。22 个月时，治疗组的平均 MBL 为 2.09 ± 1.03 毫米，对照组为 1.58 ± 0.73 毫米（p = 0.339）。在 22 个月的随访中，探诊深度 (PD) 和探诊出血量 (BOP) 也没有发现明显的统计学差异。对照组观察到软组织平均后退（0.36 ± 0.84 mm），而试验组未发现后退（p = 0.2）。33% 的测试组参与者出现了早期种植体软组织暴露，而对照组则没有（p = 0.047）：结论：种植体植入一年后，ARP 处理过的种植体与自然愈合的种植体在边缘骨吸收方面没有明显差异。不过，ARP 处理过的部位会出现早期种植体软组织暴露，这表明软组织愈合可能会受到影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical Implant Dentistry and Related Research 医学-牙科与口腔外科

CiteScore

6.00

自引率

13.90%

发文量

103

审稿时长

4-8 weeks

期刊介绍： The goal of Clinical Implant Dentistry and Related Research is to advance the scientific and technical aspects relating to dental implants and related scientific subjects. Dissemination of new and evolving information related to dental implants and the related science is the primary goal of our journal. The range of topics covered by the journals will include but be not limited to: New scientific developments relating to bone Implant surfaces and their relationship to the surrounding tissues Computer aided implant designs Computer aided prosthetic designs Immediate implant loading Immediate implant placement Materials relating to bone induction and conduction New surgical methods relating to implant placement New materials and methods relating to implant restorations Methods for determining implant stability A primary focus of the journal is publication of evidenced based articles evaluating to new dental implants, techniques and multicenter studies evaluating these treatments. In addition basic science research relating to wound healing and osseointegration will be an important focus for the journal.