Ethosome: An Innovative Perspective of Drug Delivery.

Q2 Pharmacology, Toxicology and Pharmaceutics

Pharmaceutical nanotechnology Pub Date : 2024-05-28 DOI:10.2174/0122117385303596240513053014

Nilam Santosh Lohakare, Dr Vaibhav Gulabrao Bhamare, Nikhil Dadaji Chavan, Shruti Dnyaneshwar Shelar, Harshal Dattatray Mahajan, Dr Rakesh Devidas Amrutkar

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引用次数: 0

Abstract

Ethosome offers a unique solution to the challenges faced by conventional drug delivery systems. In comparison to traditional liposomes and other nanocarriers, ethosomes exhibit a unique ability to improve drug absorption, overcoming a major limitation in the Transdermal Drug Delivery System. Their soft and flexible nano-vesicular structure facilitates faster permeation, resulting in significantly higher transdermal flux. This scientific investigation effectively traverses the changing landscape of ethosomes as an innovative drug delivery system. By conducting a thorough comparative analysis, we uncover the distinct characteristics that set them apart from other nanocarriers, offering insights into their distinct advantages. The study also includes a detailed analysis of the variables that have a complex impact on performance, elucidating transport mechanisms and addressing advanced facets pivotal for refined drug delivery strategies. This comprehensive overview highlights ethosomes as a future of medicine, offering a promising future for the safe and effective treatment of diverse diseases, impacting numerous lives.

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Ethosome：药物输送的创新视角。

乙硫体为传统给药系统所面临的挑战提供了一种独特的解决方案。与传统的脂质体和其他纳米载体相比，乙硫体具有独特的促进药物吸收的能力，克服了透皮给药系统的主要限制。其柔软而富有弹性的纳米囊泡结构有利于加快药物渗透，从而显著提高透皮通量。这项科学研究有效地揭示了乙硫体作为一种创新的给药系统所经历的风云变幻。通过全面的比较分析，我们发现了乙硫体有别于其他纳米载体的显著特点，并深入了解了它们的独特优势。本研究还详细分析了对性能产生复杂影响的变量，阐明了传输机制，并探讨了对完善给药策略至关重要的先进方面。这篇全面的综述强调了乙硫体是未来医学的发展方向，为安全有效地治疗各种疾病提供了广阔的前景，影响着无数人的生命。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Pharmaceutical nanotechnology Pharmacology, Toxicology and Pharmaceutics-Pharmaceutical Science

CiteScore

4.20

自引率

0.00%

发文量

期刊介绍： Pharmaceutical Nanotechnology publishes original manuscripts, full-length/mini reviews, thematic issues, rapid technical notes and commentaries that provide insights into the synthesis, characterisation and pharmaceutical (or diagnostic) application of materials at the nanoscale. The nanoscale is defined as a size range of below 1 µm. Scientific findings related to micro and macro systems with functionality residing within features defined at the nanoscale are also within the scope of the journal. Manuscripts detailing the synthesis, exhaustive characterisation, biological evaluation, clinical testing and/ or toxicological assessment of nanomaterials are of particular interest to the journal’s readership. Articles should be self contained, centred around a well founded hypothesis and should aim to showcase the pharmaceutical/ diagnostic implications of the nanotechnology approach. Manuscripts should aim, wherever possible, to demonstrate the in vivo impact of any nanotechnological intervention. As reducing a material to the nanoscale is capable of fundamentally altering the material’s properties, the journal’s readership is particularly interested in new characterisation techniques and the advanced properties that originate from this size reduction. Both bottom up and top down approaches to the realisation of nanomaterials lie within the scope of the journal.