Pathophysiology of cutaneous T-cell lymphomas: Perspective from a French referral centre

IF 4.3 3区 材料科学 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC
Adèle De Masson , Ingrid Lazaridou , Hélène Moins-Teisserenc , Caroline Ram-Wolff , Jérôme Giustiniani , Martine Bagot , Maxime Battistella , Armand Bensussan
{"title":"Pathophysiology of cutaneous T-cell lymphomas: Perspective from a French referral centre","authors":"Adèle De Masson ,&nbsp;Ingrid Lazaridou ,&nbsp;Hélène Moins-Teisserenc ,&nbsp;Caroline Ram-Wolff ,&nbsp;Jérôme Giustiniani ,&nbsp;Martine Bagot ,&nbsp;Maxime Battistella ,&nbsp;Armand Bensussan","doi":"10.1016/j.imlet.2024.106871","DOIUrl":null,"url":null,"abstract":"<div><p>Cutaneous T-cell lymphomas (CTCL) are a diverse group of malignant blood disorders characterized by initial skin infiltration, and sometimes, tumor spreading to lymph nodes, blood, and viscera. Mycosis fungoides is the most common form. Sézary syndrome is a distinctive form of CTCL marked by a significant presence of circulating tumor cells in peripheral blood. These diseases are characterized by the plasticity and heterogeneity of the tumor cells in the different tissue compartments, and a difficulty in identifying these tumor cells for diagnostic purposes and therapeutic monitoring. Progress has been made in the understanding of the pathophysiology of these diseases in recent years, and we provide here a review of these advancements.</p></div>","PeriodicalId":3,"journal":{"name":"ACS Applied Electronic Materials","volume":null,"pages":null},"PeriodicalIF":4.3000,"publicationDate":"2024-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"ACS Applied Electronic Materials","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0165247824000452","RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ENGINEERING, ELECTRICAL & ELECTRONIC","Score":null,"Total":0}
引用次数: 0

Abstract

Cutaneous T-cell lymphomas (CTCL) are a diverse group of malignant blood disorders characterized by initial skin infiltration, and sometimes, tumor spreading to lymph nodes, blood, and viscera. Mycosis fungoides is the most common form. Sézary syndrome is a distinctive form of CTCL marked by a significant presence of circulating tumor cells in peripheral blood. These diseases are characterized by the plasticity and heterogeneity of the tumor cells in the different tissue compartments, and a difficulty in identifying these tumor cells for diagnostic purposes and therapeutic monitoring. Progress has been made in the understanding of the pathophysiology of these diseases in recent years, and we provide here a review of these advancements.

皮肤 T 细胞淋巴瘤的病理生理学:来自法国转诊中心的视角。
皮肤T细胞淋巴瘤(CTCL)是一组种类繁多的恶性血液疾病,其特点是最初的皮肤浸润,有时肿瘤会扩散到淋巴结、血液和内脏。放线菌病是最常见的一种。塞扎里综合征(Sézary syndrome)是一种独特的 CTCL,其特征是外周血中存在大量循环肿瘤细胞。这些疾病的特点是肿瘤细胞在不同组织区划中具有可塑性和异质性,而且难以识别这些肿瘤细胞以进行诊断和治疗监测。近年来,人们在了解这些疾病的病理生理学方面取得了进展,我们在此对这些进展进行综述。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
CiteScore
7.20
自引率
4.30%
发文量
567
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信