Xiaoying Feng , Yixin Kuang , Liwu Gan , Suxin Zhou , Juan Zheng , Gangfeng Ouyang
{"title":"Solid phase microextraction for the bioanalysis of emerging organic pollutants","authors":"Xiaoying Feng , Yixin Kuang , Liwu Gan , Suxin Zhou , Juan Zheng , Gangfeng Ouyang","doi":"10.1016/j.trac.2024.117786","DOIUrl":null,"url":null,"abstract":"<div><p>Emerging organic pollutants (EOPs) are a class of hazardous and poisonous organic substances with high biotoxicity, bioaccumulation and long-term residual. They can be enriched in organisms, leading to great risks to ecosystem and human health. Therefore, it is crucial to establish sensitive and reliable analytical methods to identify and detect EOPs in biological samples. Solid phase microextraction (SPME) has been well explored as an effective, environmental-friendly and automated sample preparation technique for bioanalysis. The development of high-efficiency SPME coatings, convenient sampling approaches and practical analytical instruments significantly promotes the rapid screening and accurate determination of EOPs. This review summarizes the SPME application of diverse EOPs in complex biological matrices, and also presents <em>in vitro</em> and <em>in vivo</em> SPME for bioanalysis. In addition, the promising biocompatible coatings and recently used analytical instruments are reviewed in this work, offering new perspectives for the innovation on SPME-based bioanalytical methods.</p></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":null,"pages":null},"PeriodicalIF":11.8000,"publicationDate":"2024-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Trends in Analytical Chemistry","FirstCategoryId":"1","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0165993624002693","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, ANALYTICAL","Score":null,"Total":0}
引用次数: 0
Abstract
Emerging organic pollutants (EOPs) are a class of hazardous and poisonous organic substances with high biotoxicity, bioaccumulation and long-term residual. They can be enriched in organisms, leading to great risks to ecosystem and human health. Therefore, it is crucial to establish sensitive and reliable analytical methods to identify and detect EOPs in biological samples. Solid phase microextraction (SPME) has been well explored as an effective, environmental-friendly and automated sample preparation technique for bioanalysis. The development of high-efficiency SPME coatings, convenient sampling approaches and practical analytical instruments significantly promotes the rapid screening and accurate determination of EOPs. This review summarizes the SPME application of diverse EOPs in complex biological matrices, and also presents in vitro and in vivo SPME for bioanalysis. In addition, the promising biocompatible coatings and recently used analytical instruments are reviewed in this work, offering new perspectives for the innovation on SPME-based bioanalytical methods.
期刊介绍:
TrAC publishes succinct and critical overviews of recent advancements in analytical chemistry, designed to assist analytical chemists and other users of analytical techniques. These reviews offer excellent, up-to-date, and timely coverage of various topics within analytical chemistry. Encompassing areas such as analytical instrumentation, biomedical analysis, biomolecular analysis, biosensors, chemical analysis, chemometrics, clinical chemistry, drug discovery, environmental analysis and monitoring, food analysis, forensic science, laboratory automation, materials science, metabolomics, pesticide-residue analysis, pharmaceutical analysis, proteomics, surface science, and water analysis and monitoring, these critical reviews provide comprehensive insights for practitioners in the field.