{"title":"Inter-individual responses to arginine oral supplementation on post-exercise hypotension in treated hypertensives: A pilot study","authors":"J.V. Cavalari , A.F. Aguiar , J. Casonatto","doi":"10.1016/j.scispo.2023.01.009","DOIUrl":null,"url":null,"abstract":"<div><h3>Objective</h3><p>To analyze the inter-individual responsiveness of post-exercise hypotension after a single dose of l-arginine supplementation in hypertensive patients.</p></div><div><h3>Equipment and methods</h3><p>A double-blind, randomized, placebo-controlled crossover trial was conducted. A total of 10 adults, hypertensive and sedentary, were randomly assigned to both experimental groups (placebo and l-arginine). The participants ingested a sachet containing 8 grams of l-arginine or placebo (corn starch). During the experimental sessions, individuals performed 40<!--> <!-->min of walking/running on a treadmill at 60–70% of heart rate reserve. After the exercise sessions, blood pressure was measured every 10<!--> <!-->min for 60<!--> <!-->min.</p></div><div><h3>Results</h3><p>Considering systolic blood pressure, most participants responded favorably (lowering BP) in the “arginine” experimental arm.</p></div>","PeriodicalId":21728,"journal":{"name":"Science & Sports","volume":null,"pages":null},"PeriodicalIF":0.8000,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Science & Sports","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0765159724000479","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"SPORT SCIENCES","Score":null,"Total":0}
引用次数: 0
Abstract
Objective
To analyze the inter-individual responsiveness of post-exercise hypotension after a single dose of l-arginine supplementation in hypertensive patients.
Equipment and methods
A double-blind, randomized, placebo-controlled crossover trial was conducted. A total of 10 adults, hypertensive and sedentary, were randomly assigned to both experimental groups (placebo and l-arginine). The participants ingested a sachet containing 8 grams of l-arginine or placebo (corn starch). During the experimental sessions, individuals performed 40 min of walking/running on a treadmill at 60–70% of heart rate reserve. After the exercise sessions, blood pressure was measured every 10 min for 60 min.
Results
Considering systolic blood pressure, most participants responded favorably (lowering BP) in the “arginine” experimental arm.
期刊介绍:
Science & Sports is a peer-reviewed journal, publishing worldwide high-quality and impactful papers of medical, scientific and applied technical research in the different fields of sports and physical activities: sport medicine, exercise physiology, sport physiology and performance, nutrition, traumatology relating to sport, rehabilitation or adapted physical activities. It facilitates the transfer of knowledge and technology between the clinic, research and practice in physical and athletic activity.