DNA profiling in India: Addressing issues of sample preservation, databasing, marker selection, & statistical approaches

IF 1.9 4区医学 Q2 MEDICINE, LEGAL

Science & Justice Pub Date : 2024-05-23 DOI:10.1016/j.scijus.2024.05.003

Vivek Sahajpal , Deepika Bhandari

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引用次数: 0

Abstract

DNA technology is the gold standard with respect to the identification of individuals from biological evidence. The technology offers the convenience of a universally similar approach and methodology for analysis across the globe. However, the technology has not realised its full potential in India due to the lack of a DNA database and lacunae in sample collection and preservation from the scene of crime and victims (especially those of sexual assault). Further, statistical interpretation of DNA results is non-existent in the majority of cases. Though the latest technologies and developments in the field of DNA analysis are being adopted and implemented, very little has been enacted practically to improve optimise sample collection and preservation. This article discusses current casework scenarios that highlight the pitfalls and ambiguous areas in the field of DNA analysis, especially with respect DNA databases, sampling, and statistical approaches to genetic data analysis. Possible solutions and mitigation measures are suggested.

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印度的 DNA 分析：解决样本保存、数据库、标记选择和统计方法等问题

DNA 技术是根据生物证据鉴定个人身份的黄金标准。该技术为全球各地提供了普遍相似的分析方法和手段。然而，由于缺乏 DNA 数据库，以及在犯罪现场和受害者（尤其是性侵犯受害者）样本收集和保存方面的缺陷，该技术在印度并未充分发挥其潜力。此外，在大多数情况下，DNA 结果的统计解释也不存在。虽然 DNA 分析领域的最新技术和发展已被采用和实施，但在优化样本采集和保存方面，实际应用却很少。本文讨论了当前的一些案例，这些案例凸显了 DNA 分析领域的陷阱和模糊地带，特别是在 DNA 数据库、取样和基因数据分析统计方法方面。文章提出了可能的解决方案和缓解措施。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Science & Justice 医学-病理学

CiteScore

4.20

自引率

15.80%

发文量

审稿时长

81 days

期刊介绍： Science & Justice provides a forum to promote communication and publication of original articles, reviews and correspondence on subjects that spark debates within the Forensic Science Community and the criminal justice sector. The journal provides a medium whereby all aspects of applying science to legal proceedings can be debated and progressed. Science & Justice is published six times a year, and will be of interest primarily to practising forensic scientists and their colleagues in related fields. It is chiefly concerned with the publication of formal scientific papers, in keeping with its international learned status, but will not accept any article describing experimentation on animals which does not meet strict ethical standards. Promote communication and informed debate within the Forensic Science Community and the criminal justice sector. To promote the publication of learned and original research findings from all areas of the forensic sciences and by so doing to advance the profession. To promote the publication of case based material by way of case reviews. To promote the publication of conference proceedings which are of interest to the forensic science community. To provide a medium whereby all aspects of applying science to legal proceedings can be debated and progressed. To appeal to all those with an interest in the forensic sciences.