Anti-Urolithiasis Activity of Selected Plant Extracts by Titrimetry Method and Aggregation Assay

Siddhartha Lolla, Harika Peddinti, Sravanthi Gojuvaka, Samrin Saba, Uma Devi Dasari, Madhavi Pillalamarri
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Abstract

A major global health concern with a high recurrence rate is urolithiasis. Various in vivo and in vitro techniques have been effective in assessing the anti urolithiatic capacity of therapeutic plants. Renal stone production can be studied using in vitro models, whereas the pathological implications of urolithiasis are declared using in vivo models. Therefore, preventative management can be considerably and successfully evaluated using in vitro models, whereas urolithiasis treatment can be directed by using in vivo models. This study explains the benefits, drawbacks, and uses of both models, with a focus on the contribution of in vitro research to the assessment of preventive care. We done Physicochemical Tests for Phyllanthus acidus (fruits) Tinospora cordifolia (leaves) and Psidium gujava (fruits and leaves ) and also Preliminary Phytochemical Investigation of Phyllanthus acidus (fruits), Tinospora cordifolia (leaves) and Psidium gujava (fruits and leaves).
用滴定法和聚集测定法测定某些植物提取物的抗尿崩症活性
泌尿系统结石是全球关注的一个主要健康问题,复发率很高。各种体内和体外技术都能有效评估治疗植物的抗尿路结石能力。肾结石的产生可通过体外模型进行研究,而尿路结石的病理影响则可通过体内模型来宣布。因此,使用体外模型可以对预防性管理进行大量成功的评估,而使用体内模型则可以指导尿路结石的治疗。本研究解释了这两种模型的优点、缺点和用途,重点是体外研究对预防性治疗评估的贡献。我们对酸浆果(果实)、茵陈(叶片)和番石榴(果实和叶片)进行了理化测试,并对酸浆果(果实)、茵陈(叶片)和番石榴(果实和叶片)进行了初步的植物化学研究。
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