Design and Fabrication of Fibrous Spindle-Like Constructs Using a Melt Electrohydrodynamic Writing Process

IF 4.2 3区 材料科学 Q2 MATERIALS SCIENCE, MULTIDISCIPLINARY
Ahmadreza Zaeri, Kai Cao, Fucheng Zhang, Ralf Zgeib, Robert C. Chang
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Abstract

Advanced manufacturing of 3D-structured materials enables the production of biomimetic muscle tissues. While models of muscle tissue exist, current approaches possess a limited ability to capture essential elements of the muscle tissue microarchitecture. Therefore, this paper aims to engineer the intrinsically complex muscle spindle-like ellipsoid geometry using a polymer melt-based electrohydrodynamic (EHD) printing system. EHD systems have conventionally reported fiber deposition in a layerwise fashion. However, without mitigation, the observed fiber sagging and residual charge phenomena for the melt electrowriting (MEW) process limit the ability to produce layered fibrous 3D constructs with in-plane fiber alignment. However, in this work, fiber sagging and residual charge phenomena are leveraged as part of the design intent to deposit nonoverlapping suspended fibers between two stationary walls toward spindle-like construct fabrication. Specifically, herein the structural and mechanical properties of the MEW-enabled spindle-like constructs are analyzed as a function of the process and design parameters that govern control over fiber sagging and residual charge. The results indicate that the collector speed and wall-to-wall distance are the key parameters for tuning the spindle morphology. Moreover, cycle number and fiber diameter are identified as effective parameters for tuning the spindle mechanical properties.

Abstract Image

利用熔体电流体动力写入工艺设计和制造纤维状纺锤形构件
先进的三维结构材料制造技术可生产仿生肌肉组织。虽然已有肌肉组织模型,但目前的方法捕捉肌肉组织微观结构基本要素的能力有限。因此,本文旨在利用基于聚合物熔体的电流体动力(EHD)打印系统,设计出具有内在复杂性的肌肉纺锤形椭圆体几何结构。据报道,EHD 系统通常以分层方式沉积纤维。然而,在熔体电写入(MEW)过程中观察到的纤维下垂和残余电荷现象,如果不加以缓解,就会限制生产具有面内纤维排列的分层纤维三维结构的能力。然而,在这项工作中,纤维下垂和残余电荷现象被作为设计意图的一部分加以利用,在两个固定壁之间沉积非重叠的悬浮纤维,以实现纺锤形结构的制造。具体来说,本文分析了 MEW 所支持的类纺锤结构的结构和机械性能,并将其作为控制纤维下垂和残余电荷的工艺和设计参数的函数。结果表明,收集器速度和壁间距离是调整纺锤形态的关键参数。此外,循环次数和纤维直径也是调整锭子机械性能的有效参数。
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来源期刊
Macromolecular Materials and Engineering
Macromolecular Materials and Engineering 工程技术-材料科学:综合
CiteScore
7.30
自引率
5.10%
发文量
328
审稿时长
1.6 months
期刊介绍: Macromolecular Materials and Engineering is the high-quality polymer science journal dedicated to the design, modification, characterization, processing and application of advanced polymeric materials, including membranes, sensors, sustainability, composites, fibers, foams, 3D printing, actuators as well as energy and electronic applications. Macromolecular Materials and Engineering is among the top journals publishing original research in polymer science. The journal presents strictly peer-reviewed Research Articles, Reviews, Perspectives and Comments. ISSN: 1438-7492 (print). 1439-2054 (online). Readership:Polymer scientists, chemists, physicists, materials scientists, engineers Abstracting and Indexing Information: CAS: Chemical Abstracts Service (ACS) CCR Database (Clarivate Analytics) Chemical Abstracts Service/SciFinder (ACS) Chemistry Server Reaction Center (Clarivate Analytics) ChemWeb (ChemIndustry.com) Chimica Database (Elsevier) COMPENDEX (Elsevier) Current Contents: Physical, Chemical & Earth Sciences (Clarivate Analytics) Directory of Open Access Journals (DOAJ) INSPEC (IET) Journal Citation Reports/Science Edition (Clarivate Analytics) Materials Science & Engineering Database (ProQuest) PASCAL Database (INIST/CNRS) Polymer Library (iSmithers RAPRA) Reaction Citation Index (Clarivate Analytics) Science Citation Index (Clarivate Analytics) Science Citation Index Expanded (Clarivate Analytics) SciTech Premium Collection (ProQuest) SCOPUS (Elsevier) Technology Collection (ProQuest) Web of Science (Clarivate Analytics)
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