Comparative Study of Electrospinning Parameters for Production of Polylactic Acid and Polycaprolactone Nanofibers Based on Design of Experiment

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-05-21 DOI:10.3311/ppch.22814

Réka Barabás, Atád Vészi

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引用次数: 0

Abstract

In terms of applications, the diameter of nanofibers is one of their most important characteristics. This size is influenced by various process parameters, such as: the concentration, the distance between the needle and the collector, volume flow, etc. In this study, we compared the average diameter of nanofibers made from two different polymers, polycaprolactone and polylactic acid.We investigated the impact of various parameters on the production of nanofibers from polycaprolactone and polylactic acid using the electrospinning technique. We employed a factorial experiment design model to characterize this versatile and efficient fibre fabrication method. By considering the effects of voltage, concentration, distance between the pin and the collector, and flow rate, we established a mathematical model to describe the process. The diameters and morphologies of the resulting fibers were analyzed and compared to each other using SEM analysis. Our findings revealed that, among the studied parameters, concentration had the most significant impact on the diameter of the polymer fibers.

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基于实验设计的生产聚乳酸和聚己内酯纳米纤维的电纺丝参数比较研究

在应用方面，纳米纤维的直径是其最重要的特征之一。这种尺寸受各种工艺参数的影响，如：浓度、针与收集器之间的距离、体积流量等。在本研究中，我们比较了由聚己内酯和聚乳酸两种不同聚合物制成的纳米纤维的平均直径。我们研究了各种参数对使用电纺丝技术生产聚己内酯和聚乳酸纳米纤维的影响。我们采用了一个因子实验设计模型来描述这种多功能、高效的纤维制造方法。通过考虑电压、浓度、针与收集器之间的距离以及流速的影响，我们建立了一个数学模型来描述这一过程。通过扫描电镜分析，我们对所制备纤维的直径和形态进行了分析和比较。我们的研究结果表明，在所研究的参数中，浓度对聚合物纤维的直径影响最大。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.