Ribosome rescue factor PELOTA modulates translation start site choice for C/EBPα protein isoforms

IF 3.3 2区生物学 Q1 BIOLOGY

Life Science Alliance Pub Date : 2024-05-21 DOI:10.26508/lsa.202302501

Samantha G. Fernandez, Lucas Ferguson, Nicholas T. Ingolia

引用次数: 0

Abstract

Alternative translation initiation on a single mRNA can generate distinct protein isoforms. This work finds that the ribosome rescue factor, PELOTA, influences start site choice on the developmental transcription factor, C/EBPα.

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核糖体拯救因子 PELOTA 可调节 C/EBPα 蛋白同工酶翻译起始位点的选择

单个 mRNA 的替代翻译起始可产生不同的蛋白质异构体。这项研究发现，核糖体拯救因子 PELOTA 会影响发育转录因子 C/EBPα 的起始位点选择。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Life Science Alliance Agricultural and Biological Sciences-Plant Science

CiteScore

5.80

自引率

2.30%

发文量

241

审稿时长

10 weeks

期刊介绍： Life Science Alliance is a global, open-access, editorially independent, and peer-reviewed journal launched by an alliance of EMBO Press, Rockefeller University Press, and Cold Spring Harbor Laboratory Press. Life Science Alliance is committed to rapid, fair, and transparent publication of valuable research from across all areas in the life sciences.