Takayasu Arteritis Associated with Ulcerative Colitis: Literature Review of HLA Profile

Abstract

Takayasu arteritis and ulcerative colitis are two chronic inflammatory diseases of unknown etiology and their coexistence is very rare. In this report, we describe a case of 51 years-old Moroccan man with a 4 years history of ulcerative colitis confirmed with pathologic examination who developed Takayasu arteritis. The patient was admitted several times for recurrent arterial and venous thrombosis; during the etiologic investigation, Takayasu's arteritis was diagnosed. The coexistence of these two pathologies is a rare entity, reported accidentally in the world especially in Southeast Asia. This association supposed common pathophysiological mechanisms. Different assumptions, genetic factors and environmental agents that contribute to the pathogenesis of these diseases, have to be validated by others studies to clarify these mechanisms.