Momordica charantia Leaf Extract Mediated Zinc Oxide Nanoparticles for Antibacterial Performance

P. Subramanian, S. Alwin David
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Abstract

We uncovered a simple and conservational process for the production of zinc oxide nanoparticles (ZnO NPs). This was accomplished by a biosynthetic method that included the leaf extract of Momordica charantia as a reducing agent. The UV-Vis absorption spectrum of them exhibits maxima at 352 nm. The presence of bands at 630cm-1 in the Fourier transform infrared spectrum verifies the production of zinc oxide nanoparticles. XRD determined that the particle size ranged between 20 and 58nm. Field emission scanning electron microscopy exposed that the ZnO NPs were irregular in nature and ranged in size from 20 to 60nm. The existence of oxygen and zinc in ZnO NPs is verified by energy-dispersive X-ray analysis. ZnO NPs exhibited strong antibacterial action against Klebsiella pneumoniae and Staphylococcus aureus. This biosynthetic technique could pave the way for simple, cost-effective, environmentally friendly products that avoid toxic chemicals and are helpful for applications in medication and the large-scale manufacture of nanoparticles.
以黑千层叶提取物为介导的纳米氧化锌抗菌剂
我们发现了一种生产氧化锌纳米粒子(ZnO NPs)的简单而环保的工艺。这是通过一种生物合成方法实现的,其中包括作为还原剂的 Momordica charantia 叶提取物。它们的紫外可见吸收光谱在 352 纳米处显示出最大值。傅立叶变换红外光谱中 630cm-1 处的条带证实了氧化锌纳米粒子的生成。X 射线衍射仪测定的粒度在 20 至 58 纳米之间。场发射扫描电子显微镜显示,氧化锌纳米粒子呈不规则状,大小在 20 至 60 纳米之间。能量色散 X 射线分析验证了氧化锌纳米粒子中氧和锌的存在。ZnO NPs 对肺炎克雷伯氏菌和金黄色葡萄球菌有很强的抗菌作用。这种生物合成技术可为生产简单、经济、环保的产品铺平道路,避免使用有毒化学物质,有助于药物应用和纳米粒子的大规模生产。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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