{"title":"Recent advances in photo‐responsive carbon dots for tumor therapy","authors":"Huiqi Zhang, Yupeng Liu, Songnan Qu","doi":"10.1002/rpm.20240012","DOIUrl":null,"url":null,"abstract":"The precision treatment of tumors with minimal side effects is associated with improved human health and quality of life. In recent years, phototherapy has attracted significant attention in tumor therapy due to its versatility, spatiotemporal controllability, non‐resistance, and minimal side effects. Carbon dots (CDs) are considered promising phototherapy reagents because of their simple preparation, facilitated surface modification, tunable energy bands, excellent electron‐transfer capabilities, remarkable photoelectric and photothermal conversion properties, and outstanding biocompatibility. This review summarizes recent advancements in photo‐responsive CDs for photodynamic therapy and the emerging photocatalytic therapy of tumors. Finally, the article discusses the main challenges associated with the development of photo‐responsive CDs for oncology therapeutics and strategies to overcome these challenges.","PeriodicalId":313882,"journal":{"name":"Responsive Materials","volume":"15 2","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Responsive Materials","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1002/rpm.20240012","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
The precision treatment of tumors with minimal side effects is associated with improved human health and quality of life. In recent years, phototherapy has attracted significant attention in tumor therapy due to its versatility, spatiotemporal controllability, non‐resistance, and minimal side effects. Carbon dots (CDs) are considered promising phototherapy reagents because of their simple preparation, facilitated surface modification, tunable energy bands, excellent electron‐transfer capabilities, remarkable photoelectric and photothermal conversion properties, and outstanding biocompatibility. This review summarizes recent advancements in photo‐responsive CDs for photodynamic therapy and the emerging photocatalytic therapy of tumors. Finally, the article discusses the main challenges associated with the development of photo‐responsive CDs for oncology therapeutics and strategies to overcome these challenges.
以最小的副作用精准治疗肿瘤与改善人类健康和生活质量息息相关。近年来,光疗因其多功能性、时空可控性、无抗药性和副作用小等特点,在肿瘤治疗领域备受关注。碳点(CD)因其制备简单、表面改性方便、能带可调、电子转移能力强、光电和光热转换性能显著以及生物相容性好而被认为是有前途的光疗试剂。这篇综述总结了用于光动力疗法和新兴肿瘤光催化疗法的光响应 CD 的最新进展。最后,文章讨论了开发用于肿瘤治疗的光响应 CD 所面临的主要挑战以及克服这些挑战的策略。