{"title":"Carbonylative synthesis of versatile α-(Silyl)acetates and its diverse transformations","authors":"Le-Cheng Wang , Yang Yuan , Xiao-Feng Wu","doi":"10.1016/j.jcat.2024.115568","DOIUrl":null,"url":null,"abstract":"<div><p>α-(Silyl)acetates are a class of stable and versatile organosilicon compounds wherein the inherent diversity of silicon can be exploited to unlock reactivity through masked carbanions, carbon nucleophiles, carbon-centered radical intermediates, and silicon electrophiles. Hence the developing of new methodology for their preparation is important and attractive. Herein, we developed an efficient method for the carbonylative synthesis of versatile α-(silyl)acetates. The reaction features simple operation, mild conditions, broad substrate scope, and good functional group tolerance. The α-(silyl)acetates prepared showed excellent reactivity in a series of transformations, highlighting the synthetic utility of this strategy.</p></div>","PeriodicalId":346,"journal":{"name":"Journal of Catalysis","volume":null,"pages":null},"PeriodicalIF":6.5000,"publicationDate":"2024-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Catalysis","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0021951724002811","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, PHYSICAL","Score":null,"Total":0}
引用次数: 0
Abstract
α-(Silyl)acetates are a class of stable and versatile organosilicon compounds wherein the inherent diversity of silicon can be exploited to unlock reactivity through masked carbanions, carbon nucleophiles, carbon-centered radical intermediates, and silicon electrophiles. Hence the developing of new methodology for their preparation is important and attractive. Herein, we developed an efficient method for the carbonylative synthesis of versatile α-(silyl)acetates. The reaction features simple operation, mild conditions, broad substrate scope, and good functional group tolerance. The α-(silyl)acetates prepared showed excellent reactivity in a series of transformations, highlighting the synthetic utility of this strategy.
期刊介绍：
The Journal of Catalysis publishes scholarly articles on both heterogeneous and homogeneous catalysis, covering a wide range of chemical transformations. These include various types of catalysis, such as those mediated by photons, plasmons, and electrons. The focus of the studies is to understand the relationship between catalytic function and the underlying chemical properties of surfaces and metal complexes.
The articles in the journal offer innovative concepts and explore the synthesis and kinetics of inorganic solids and homogeneous complexes. Furthermore, they discuss spectroscopic techniques for characterizing catalysts, investigate the interaction of probes and reacting species with catalysts, and employ theoretical methods.
The research presented in the journal should have direct relevance to the field of catalytic processes, addressing either fundamental aspects or applications of catalysis.
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