Prevalence of Erectile Dysfunction among Patients with Coronary Artery Disease

IF 2.1 4区 医学 Q3 ANDROLOGY
Andrologia Pub Date : 2024-03-25 DOI:10.1155/2024/6151669
Islam Mohamed Abd Elsamie, Hassan Abou Khodair, Mohamed Sayed Bashandy, Hany Aboelwafa
{"title":"Prevalence of Erectile Dysfunction among Patients with Coronary Artery Disease","authors":"Islam Mohamed Abd Elsamie,&nbsp;Hassan Abou Khodair,&nbsp;Mohamed Sayed Bashandy,&nbsp;Hany Aboelwafa","doi":"10.1155/2024/6151669","DOIUrl":null,"url":null,"abstract":"<p>Both coronary artery disease (CAD) and erectile dysfunction (ED) are widespread illnesses that frequently coexist. Numerous triggering risk factors and pathophysiological mechanisms contribute to both diseases. Penile color Doppler ultrasound can serve as a crucial tool to evaluate penile arterial blood flow. Therefore, this study aims to assess the ED prevalence in CAD patients, to determine the socioeconomic and clinical profiles of the population, and to define risk factors of their development. The cross-sectional study included 100 male patients who were admitted to the coronary angiography (CAG) unit. Patients were asked if they had ED, and if present, it was graded using the International Index of Erectile Function 5. Right and left cavernosal arteries were examined using color Doppler and erection hardness to assess the peak systolic velocity (PSV) and end-diastolic velocity. Among the 52 cases that suffered from ED, most of the cases had mild grades (38.5%). All cases without ED (100%) had penile artery Doppler PSV findings ≥30 (cm/s) with an average Doppler PSV of 48.02 ± 7.49 cm/s for the right cavernosal arteries and 47.4 ± 7.17 cm/s for the left cavernosal arteries. Yet, 71.2% of cases with ED had penile artery Doppler PSV findings &lt;30 (cm/s) with an average Doppler PSV of 29.1 ± 7.57 cm/s for the right cavernosal arteries and 28.69 ± 7.11 cm/s for the left cavernosal arteries. Furthermore, by CAG, 50% of cases without ED had blockage not necessitating a coronary intervention (no significant disease) compared to 25% of cases with ED. There was positive correlation between advanced grade of ED and age (<i>r</i> = 0.327, <i>P</i>  &lt; 0.001), hypertension (<i>r</i> = 0.213, <i>P</i> = 0.033), DM (<i>r</i> = 0.253, <i>P</i> = 0.011), smoking (<i>r</i> = 0.202, <i>P</i> = 0.044), and severity of CAD (<i>r</i> = 0.332, <i>P</i>  &lt; 0.001). Patients with multivessel CAD have a significantly higher incidence and more severity of ED. Moreover, pathological penile vessels PSV (&lt;25 or &lt;30 cm/s) via Doppler ultrasound is mostly valuable as a noninvasive tool to define ED attributable to vascular impairment that may be antecedent to atherosclerosis in the coronary vessels.</p>","PeriodicalId":7817,"journal":{"name":"Andrologia","volume":"2024 1","pages":""},"PeriodicalIF":2.1000,"publicationDate":"2024-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Andrologia","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1155/2024/6151669","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"ANDROLOGY","Score":null,"Total":0}
引用次数: 0

Abstract

Both coronary artery disease (CAD) and erectile dysfunction (ED) are widespread illnesses that frequently coexist. Numerous triggering risk factors and pathophysiological mechanisms contribute to both diseases. Penile color Doppler ultrasound can serve as a crucial tool to evaluate penile arterial blood flow. Therefore, this study aims to assess the ED prevalence in CAD patients, to determine the socioeconomic and clinical profiles of the population, and to define risk factors of their development. The cross-sectional study included 100 male patients who were admitted to the coronary angiography (CAG) unit. Patients were asked if they had ED, and if present, it was graded using the International Index of Erectile Function 5. Right and left cavernosal arteries were examined using color Doppler and erection hardness to assess the peak systolic velocity (PSV) and end-diastolic velocity. Among the 52 cases that suffered from ED, most of the cases had mild grades (38.5%). All cases without ED (100%) had penile artery Doppler PSV findings ≥30 (cm/s) with an average Doppler PSV of 48.02 ± 7.49 cm/s for the right cavernosal arteries and 47.4 ± 7.17 cm/s for the left cavernosal arteries. Yet, 71.2% of cases with ED had penile artery Doppler PSV findings <30 (cm/s) with an average Doppler PSV of 29.1 ± 7.57 cm/s for the right cavernosal arteries and 28.69 ± 7.11 cm/s for the left cavernosal arteries. Furthermore, by CAG, 50% of cases without ED had blockage not necessitating a coronary intervention (no significant disease) compared to 25% of cases with ED. There was positive correlation between advanced grade of ED and age (r = 0.327, P  < 0.001), hypertension (r = 0.213, P = 0.033), DM (r = 0.253, P = 0.011), smoking (r = 0.202, P = 0.044), and severity of CAD (r = 0.332, P  < 0.001). Patients with multivessel CAD have a significantly higher incidence and more severity of ED. Moreover, pathological penile vessels PSV (<25 or <30 cm/s) via Doppler ultrasound is mostly valuable as a noninvasive tool to define ED attributable to vascular impairment that may be antecedent to atherosclerosis in the coronary vessels.

冠心病患者勃起功能障碍的患病率
冠状动脉疾病(CAD)和勃起功能障碍(ED)是经常并存的广泛疾病。这两种疾病的诱发危险因素和病理生理机制众多。阴茎彩色多普勒超声是评估阴茎动脉血流的重要工具。因此,本研究旨在评估 CAD 患者的 ED 患病率,确定人群的社会经济和临床概况,并界定其发病的风险因素。这项横断面研究包括 100 名入住冠状动脉造影(CAG)室的男性患者。研究人员询问患者是否患有 ED,如果存在,则使用国际勃起功能指数 5 对其进行分级。使用彩色多普勒和勃起硬度检查左右海绵体动脉,以评估收缩峰值速度(PSV)和舒张末期速度。在 52 例患有 ED 的病例中,大多数病例的程度较轻(38.5%)。所有未患 ED 的病例(100%)阴茎动脉多普勒 PSV 结果均≥30(cm/s),右侧阴茎海绵体动脉多普勒 PSV 平均值为 48.02 ± 7.49 cm/s,左侧阴茎海绵体动脉多普勒 PSV 平均值为 47.4 ± 7.17 cm/s。然而,71.2%的ED病例的阴茎动脉多普勒PSV结果为<30(cm/s),右侧阴茎海绵体动脉的多普勒PSV平均值为(29.1±7.57)cm/s,左侧阴茎海绵体动脉的多普勒PSV平均值为(28.69±7.11)cm/s。此外,在CAG中,50%无ED的病例存在无需冠状动脉介入治疗的阻塞(无明显病变),而有ED的病例只有25%。ED 的晚期程度与年龄(r = 0.327,P <0.001)、高血压(r = 0.213,P = 0.033)、糖尿病(r = 0.253,P = 0.011)、吸烟(r = 0.202,P = 0.044)和 CAD 的严重程度(r = 0.332,P <0.001)呈正相关。多血管 CAD 患者的 ED 发生率和严重程度明显更高。此外,通过多普勒超声检测病理阴茎血管PSV(25或30厘米/秒)作为一种无创工具,在确定ED归因于血管损伤(可能是冠状动脉粥样硬化的先兆)时非常有价值。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Andrologia
Andrologia 医学-男科学
CiteScore
5.60
自引率
8.30%
发文量
292
审稿时长
6 months
期刊介绍: Andrologia provides an international forum for original papers on the current clinical, morphological, biochemical, and experimental status of organic male infertility and sexual disorders in men. The articles inform on the whole process of advances in andrology (including the aging male), from fundamental research to therapeutic developments worldwide. First published in 1969 and the first international journal of andrology, it is a well established journal in this expanding area of reproductive medicine.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信