A scoping review of bacterial resistance among inpatients amidst the COVID-19 pandemic

IF 3.7 3区 医学 Q2 INFECTIOUS DISEASES
Noora Reffat , Rebecca J. Schwei , Meggie Griffin , Aurora Pop-Vicas , Lucas T. Schulz , Michael S. Pulia
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引用次数: 0

Abstract

Objectives

The COVID-19 pandemic disrupted antimicrobial stewardship and infection prevention operations worldwide, raising concerns for an acceleration of antimicrobial resistance (AMR). Therefore, we aimed to define the scope of peer reviewed research comparing AMR in inpatient bacterial clinical cultures before and after the start of the COVID-19 pandemic.

Methods

We conducted a scoping review and searched PubMed, Scopus, and Web of Science through 15 June 2023. Our inclusion criteria were: (1) English language, (2) primary evidence, (3) peer-reviewed, (4) clinical culture data from humans, (5) AMR data for at least one bacterial order/species, (6) inpatient setting, (7) use of statistical testing to evaluate AMR data before and during the COVID-19 pandemic. Reviewers extracted country, study design, type of analysis, study period, setting and population, number of positive cultures or isolates, culture type(s), method of AMR analysis, organisms, and AMR results. Study results were organised by organism and antibiotic class or resistance mechanism. AMR results are also summarised by individual study and across all studies.

Results

In total, 4805 articles were identified with 55 papers meeting inclusion criteria. Acinetobacter baumannii, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, and Staphylococcus aureus were the most commonly studied organisms. There were 464 bacterial AMR results across all studies with 82 (18%) increase, 71 (15%) decrease, and 311 (67%) no change results.

Conclusions

The literature examining the impact of COVID-19 on AMR among inpatients is diverse with most results reflecting no change pre/post pandemic. Ongoing inquiry is needed into evolving patterns in AMR post COVID-19.

Abstract Image

对 COVID-19 大流行期间住院病人细菌耐药性的范围审查。
背景:COVID-19 大流行扰乱了全球的抗菌药物管理和感染预防工作,引发了对抗菌药物耐药性(AMR)加速的担忧。因此,我们旨在确定同行评审研究的范围,比较 COVID-19 大流行开始前后住院患者细菌临床培养物中的 AMR:我们进行了一次范围界定审查,并检索了 PubMed、Scopus 和 Web of Science(截至 2023 年 6 月 15 日)。我们的纳入标准是(1) 英语;(2) 主要证据;(3) 同行评议;(4) 人类临床培养数据;(5) 至少一种细菌顺序/种类的 AMR 数据;(6) 住院环境;(7) 使用统计测试评估 COVID-19 大流行之前和期间的 AMR 数据。审稿人提取了国家、研究设计、分析类型、研究时间、环境和人群、阳性培养物或分离物的数量、培养类型、AMR 分析方法、生物体和 AMR 结果。研究结果按生物体和抗生素类别或耐药机制分类。AMR 结果还按单项研究和所有研究进行了汇总:结果:共发现 4 805 篇文章,其中 55 篇符合纳入标准。鲍曼不动杆菌、大肠埃希菌、肺炎克雷伯菌、铜绿假单胞菌和金黄色葡萄球菌是最常被研究的细菌。所有研究共得出 464 项细菌 AMR 结果,其中 82 项(18%)增加,71 项(15%)减少,311 项(67%)无变化:结论:研究 COVD-19 对住院患者 AMR 影响的文献多种多样,大多数结果显示大流行前后没有变化。需要继续调查研究 COVID-19 后 AMR 的演变模式。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of global antimicrobial resistance
Journal of global antimicrobial resistance INFECTIOUS DISEASES-PHARMACOLOGY & PHARMACY
CiteScore
8.70
自引率
2.20%
发文量
285
审稿时长
34 weeks
期刊介绍: The Journal of Global Antimicrobial Resistance (JGAR) is a quarterly online journal run by an international Editorial Board that focuses on the global spread of antibiotic-resistant microbes. JGAR is a dedicated journal for all professionals working in research, health care, the environment and animal infection control, aiming to track the resistance threat worldwide and provides a single voice devoted to antimicrobial resistance (AMR). Featuring peer-reviewed and up to date research articles, reviews, short notes and hot topics JGAR covers the key topics related to antibacterial, antiviral, antifungal and antiparasitic resistance.
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