Management of chronic kidney disease: The current novel and forgotten therapies

IF 4.2 Q1 ENDOCRINOLOGY & METABOLISM
Ákos Géza Pethő , Mihály Tapolyai , Éva Csongrádi , Petronella Orosz
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Abstract

Chronic kidney disease (CKD) is a progressive and incurable condition that imposes a significant burden on an aging society. Although the exact prevalence of this disease is unknown, it is estimated to affect at least 800 million people worldwide. Patients with diabetes or hypertension are at a higher risk of developing chronic kidney damage. As the kidneys play a crucial role in vital physiological processes, damage to these organs can disrupt the balance of water and electrolytes, regulation of blood pressure, elimination of toxins, and metabolism of vitamin D. Early diagnosis is paramount to prevent potential complications. Treatment options such as dietary modifications and medications can help slow disease progression. In our narrative review, we have summarized the available therapeutic options to slow the progression of chronic kidney disease. Many new drug treatments have recently become available, offering a beacon of hope and optimism in CKD management. Nonetheless, disease prevention remains the most critical step in disease management. Given the significant impact of CKD on public health, there is a pressing need for further research. With the development of new technologies and advancements in medical knowledge, we hope to find more effective diagnostic tools and treatments for CKD patients.

慢性肾脏病的治疗:当前的新疗法和被遗忘的疗法
慢性肾脏病(CKD)是一种渐进性的不治之症,给老龄化社会带来沉重负担。虽然这种疾病的确切发病率尚不清楚,但估计全球至少有 8 亿人患有这种疾病。糖尿病或高血压患者发生慢性肾损伤的风险较高。由于肾脏在重要的生理过程中起着至关重要的作用,这些器官的损伤会破坏水和电解质的平衡、血压的调节、毒素的排出和维生素 D 的代谢。饮食调整和药物治疗等治疗方案有助于延缓疾病的进展。在叙述性综述中,我们总结了减缓慢性肾脏病进展的现有治疗方案。最近出现了许多新的药物治疗方法,为慢性肾脏病的治疗带来了希望和乐观。然而,疾病预防仍然是疾病管理中最关键的一步。鉴于慢性肾功能衰竭对公众健康的重大影响,我们迫切需要开展进一步的研究。随着新技术的发展和医学知识的进步,我们希望能为慢性肾脏病患者找到更有效的诊断工具和治疗方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
6.10
自引率
0.00%
发文量
24
审稿时长
16 weeks
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