SARS-CoV-2 and Dysphagia: A Retrospective Analysis of COVID-19 Patients with Swallowing Disorders.

IF 2.2 3区医学 Q1 OTORHINOLARYNGOLOGY

Dysphagia Pub Date : 2025-02-01 Epub Date: 2024-05-23 DOI:10.1007/s00455-024-10715-0

Christopher Molino, Laura Bergantini, Silvia Santucci, Marialuigia Tomai Pitinca, Miriana d'Alessandro, Paolo Cameli, Sabrina Taddei, Elena Bargagli

{"title":"SARS-CoV-2 and Dysphagia: A Retrospective Analysis of COVID-19 Patients with Swallowing Disorders.","authors":"Christopher Molino, Laura Bergantini, Silvia Santucci, Marialuigia Tomai Pitinca, Miriana d'Alessandro, Paolo Cameli, Sabrina Taddei, Elena Bargagli","doi":"10.1007/s00455-024-10715-0","DOIUrl":null,"url":null,"abstract":"Background: COVID-19 can lead to impairment of neural networks involved in swallowing, since the act of swallowing is coordinated and performed by a diffuse brain network involving peripheral nerves and muscles. Dysphagia has been identified as a risk and predictive factor for the severest form of SARS-CoV-2 infection.Objectives: To investigate the association between swallowing disorders and COVID-19 in patients hospitalized for COVID-19.Methods: We collected demographic data, medical information specific to dysphagia and data on medical treatments of patients with COVID-19.Results: A total of 43 hospitalized COVID-19 patients were enrolled in the study. Twenty (46%) were evaluated positive for dysphagia and 23 (54%) were evaluated negative. Neurocognitive disorders and diabetes were mostly associated with patients who resulted positive for dysphagia. Respiratory impairment caused by COVID-19 seems to be a cause of dysphagia, since all patients who needed oxygen-therapy developed symptoms of dysphagia, unlike patients who did not. In the dysphagic group, alteration of the swallowing trigger resulted in the severest form of dysphagia. An association was found between the severest form of COVID-19 and dysphagia. This group consisted predominantly of males with longer hospitalization.Conclusions: Identification of COVID-19 patients at risk for dysphagia is crucial for better patient management.","PeriodicalId":11508,"journal":{"name":"Dysphagia","volume":" ","pages":"162-168"},"PeriodicalIF":2.2000,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11762431/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Dysphagia","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s00455-024-10715-0","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/5/23 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"OTORHINOLARYNGOLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Background: COVID-19 can lead to impairment of neural networks involved in swallowing, since the act of swallowing is coordinated and performed by a diffuse brain network involving peripheral nerves and muscles. Dysphagia has been identified as a risk and predictive factor for the severest form of SARS-CoV-2 infection.

Objectives: To investigate the association between swallowing disorders and COVID-19 in patients hospitalized for COVID-19.

Methods: We collected demographic data, medical information specific to dysphagia and data on medical treatments of patients with COVID-19.

Results: A total of 43 hospitalized COVID-19 patients were enrolled in the study. Twenty (46%) were evaluated positive for dysphagia and 23 (54%) were evaluated negative. Neurocognitive disorders and diabetes were mostly associated with patients who resulted positive for dysphagia. Respiratory impairment caused by COVID-19 seems to be a cause of dysphagia, since all patients who needed oxygen-therapy developed symptoms of dysphagia, unlike patients who did not. In the dysphagic group, alteration of the swallowing trigger resulted in the severest form of dysphagia. An association was found between the severest form of COVID-19 and dysphagia. This group consisted predominantly of males with longer hospitalization.

Conclusions: Identification of COVID-19 patients at risk for dysphagia is crucial for better patient management.

查看原文本刊更多论文

SARS-CoV-2 与吞咽困难：对 COVID-19 吞咽困难患者的回顾性分析。

背景：COVID-19可导致与吞咽有关的神经网络受损，因为吞咽动作是由涉及外周神经和肌肉的弥漫性大脑网络协调和完成的。吞咽困难已被确定为最严重的 SARS-CoV-2 感染的风险和预测因素：调查因 COVID-19 而住院的患者吞咽障碍与 COVID-19 之间的关联：方法：我们收集了COVID-19患者的人口统计学数据、吞咽困难的具体医疗信息和医疗治疗数据：共有 43 名 COVID-19 住院患者参与了研究。20例（46%）被评估为吞咽困难阳性，23例（54%）被评估为阴性。吞咽困难阳性患者多伴有神经认知障碍和糖尿病。由 COVID-19 引起的呼吸障碍似乎是导致吞咽困难的一个原因，因为所有需要氧疗的患者都出现了吞咽困难的症状，而不需要氧疗的患者则不同。在吞咽困难组中，吞咽触发器的改变导致了最严重的吞咽困难。研究发现，COVID-19 的最严重形式与吞咽困难之间存在关联。这组患者主要为男性，住院时间较长：结论：识别有吞咽困难风险的 COVID-19 患者对于更好地管理患者至关重要。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Dysphagia 医学-耳鼻喉科学

CiteScore

4.90

自引率

15.40%

发文量

149

审稿时长

6-12 weeks

期刊介绍： Dysphagia aims to serve as a voice for the benefit of the patient. The journal is devoted exclusively to swallowing and its disorders. The purpose of the journal is to provide a source of information to the flourishing dysphagia community. Over the past years, the field of dysphagia has grown rapidly, and the community of dysphagia researchers have galvanized with ambition to represent dysphagia patients. In addition to covering a myriad of disciplines in medicine and speech pathology, the following topics are also covered, but are not limited to: bio-engineering, deglutition, esophageal motility, immunology, and neuro-gastroenterology. The journal aims to foster a growing need for further dysphagia investigation, to disseminate knowledge through research, and to stimulate communication among interested professionals. The journal publishes original papers, technical and instrumental notes, letters to the editor, and review articles.