A patient-designed integrative oncology intervention for stage IV locally recurrent rectal cancer: A case report

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-05-21 DOI:10.1016/j.explore.2024.05.002

Julia M. Hush , Daniel Steffens , Michael J. Solomon

{"title":"A patient-designed integrative oncology intervention for stage IV locally recurrent rectal cancer: A case report","authors":"Julia M. Hush , Daniel Steffens , Michael J. Solomon","doi":"10.1016/j.explore.2024.05.002","DOIUrl":null,"url":null,"abstract":"<div><h3>Introduction</h3><p>Stage IV colorectal cancer is a highly challenging condition to treat, with 5-year survival rates of 13% in Australia, improving to 40% for those patients with locally recurrent rectal cancer who are suitable for total neoadjuvant therapy and pelvic exenterative surgery. This study reports a unique case of a patient with Stage IV locally recurrent rectal cancer (LRRC), who designed and implemented a holistic integrative oncology intervention.</p></div><div><h3>Case presentation</h3><p>The patient was 59-years-old when diagnosed with Stage IV locally recurrent rectal cancer, and referred to a highly specialised centre for colorectal cancer care at a tertiary teaching hospital in Sydney, Australia. Treatment included chemo/radiotherapy, liver resection and posterior pelvic exenteration surgery. The patient's background as a health researcher and clinician optimised her ability to design and implement an integrative oncology model of care, including yoga, mindfulness, Buddhist meditation and study, social connection, exercise, psychotherapeutic and nutritional support. This paper describes these mind-body practices and lifestyle modifications and outlines her experiences and outcomes at each stage of her extensive and radical treatment.</p></div><div><h3>Conclusion</h3><p>This case provides a unique perspective into how the integration of mind-body practices and lifestyle modifications with conventional treatment can support those living with colorectal cancer.</p></div>","PeriodicalId":1,"journal":{"name":"Accounts of Chemical Research","volume":null,"pages":null},"PeriodicalIF":16.4000,"publicationDate":"2024-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1550830724000843/pdfft?md5=1ea7db3899b89dba27dd4ff0d8e25931&pid=1-s2.0-S1550830724000843-main.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Accounts of Chemical Research","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1550830724000843","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}

引用次数: 0

Abstract

Introduction

Stage IV colorectal cancer is a highly challenging condition to treat, with 5-year survival rates of 13% in Australia, improving to 40% for those patients with locally recurrent rectal cancer who are suitable for total neoadjuvant therapy and pelvic exenterative surgery. This study reports a unique case of a patient with Stage IV locally recurrent rectal cancer (LRRC), who designed and implemented a holistic integrative oncology intervention.

Case presentation

The patient was 59-years-old when diagnosed with Stage IV locally recurrent rectal cancer, and referred to a highly specialised centre for colorectal cancer care at a tertiary teaching hospital in Sydney, Australia. Treatment included chemo/radiotherapy, liver resection and posterior pelvic exenteration surgery. The patient's background as a health researcher and clinician optimised her ability to design and implement an integrative oncology model of care, including yoga, mindfulness, Buddhist meditation and study, social connection, exercise, psychotherapeutic and nutritional support. This paper describes these mind-body practices and lifestyle modifications and outlines her experiences and outcomes at each stage of her extensive and radical treatment.

Conclusion

This case provides a unique perspective into how the integration of mind-body practices and lifestyle modifications with conventional treatment can support those living with colorectal cancer.

查看原文本刊更多论文

针对 IV 期局部复发直肠癌的患者设计的综合肿瘤学干预：病例报告。

简介IV期结直肠癌是一种极具治疗挑战性的疾病，在澳大利亚，5年生存率仅为13%，而对于适合接受全新药辅助治疗和盆腔肠外手术的局部复发直肠癌患者，5年生存率可提高至40%。本研究报告了一例独特的 IV 期局部复发直肠癌（LRRC）患者的病例，该患者设计并实施了整体综合肿瘤学干预：患者被诊断为局部复发直肠癌 IV 期时 59 岁，并被转诊至澳大利亚悉尼一家三级教学医院的结直肠癌高度专业化治疗中心。治疗包括化疗/放疗、肝脏切除和后盆腔开腹手术。患者的健康研究员和临床医生背景使她有能力设计并实施一种综合肿瘤治疗模式，包括瑜伽、正念、佛教冥想和学习、社会联系、运动、心理治疗和营养支持。本文介绍了这些身心练习和生活方式调整，并概述了她在广泛而彻底的治疗过程中每个阶段的经历和结果：本病例提供了一个独特的视角，让我们了解如何将身心疗法和生活方式调整与常规治疗相结合，为结肠直肠癌患者提供支持。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.