Focus on oliguria during renal replacement therapy.

IF 2.8 3区 医学 Q2 ANESTHESIOLOGY
Journal of Anesthesia Pub Date : 2024-10-01 Epub Date: 2024-05-22 DOI:10.1007/s00540-024-03342-4
Qian Zhang, Xiaoting Wang, Yangong Chao, Lixia Liu
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引用次数: 0

Abstract

Oliguria is a clinical symptom characterized by decreased urine output, which can occur at any stage of acute kidney injury and also during renal replacement therapy. In some cases, oliguria may resolve with adjustment of blood purification dose or fluid management, while in others, it may suggest a need for further evaluation and intervention. It is important to determine the underlying cause of oliguria during renal replacement therapy and to develop an appropriate treatment plan. This review looks into the mechanisms of urine production to investigate the mechanism of oliguria during renal replacement therapy from two aspects: diminished glomerular filtration rate and tubular abnormalities. The above conditions all implying a renal oxygen supply-demand imbalance, which is the signal of worsening kidney injury. It also proposes a viable clinical pathway for the treatment and management of patients with acute kidney injury receiving renal replacement therapy.

Abstract Image

关注肾脏替代疗法期间的少尿问题。
少尿是一种以尿量减少为特征的临床症状,可发生在急性肾损伤的任何阶段以及肾替代治疗期间。在某些情况下,少尿可能会在调整血液净化剂量或液体管理后缓解,而在其他情况下,少尿可能提示需要进一步评估和干预。确定肾脏替代疗法期间出现少尿的根本原因并制定适当的治疗方案非常重要。本综述探讨尿液产生的机制,从肾小球滤过率降低和肾小管异常两个方面研究肾替代治疗期间少尿的机制。上述情况均意味着肾脏氧供需失衡,是肾损伤恶化的信号。该研究还为接受肾替代治疗的急性肾损伤患者的治疗和管理提出了可行的临床路径。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of Anesthesia
Journal of Anesthesia 医学-麻醉学
CiteScore
5.30
自引率
7.10%
发文量
112
审稿时长
3-8 weeks
期刊介绍: The Journal of Anesthesia is the official journal of the Japanese Society of Anesthesiologists. This journal publishes original articles, review articles, special articles, clinical reports, short communications, letters to the editor, and book and multimedia reviews. The editors welcome the submission of manuscripts devoted to anesthesia and related topics from any country of the world. Membership in the Society is not a prerequisite. The Journal of Anesthesia (JA) welcomes case reports that show unique cases in perioperative medicine, intensive care, emergency medicine, and pain management.
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