Understanding photoacoustic signal formation in the presence of transparent thin films

IF 7.1 1区 医学 Q1 ENGINEERING, BIOMEDICAL
Maksym Illienko , Matthias C. Velsink , Stefan Witte
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引用次数: 0

Abstract

Strain-induced variation of the refractive index is the main mechanism of strain detection in photoacoustic experiments. However, weak strain-optic coupling in many materials limits the application of photoacoustics as an imaging tool. A straightforward deposition of a transparent thin film as a top layer has previously been shown to provide signal enhancement due to elastic boundary effects. In this paper, we study photoacoustic signal formation in metal covered by thin transparent films of different thicknesses and demonstrate that in addition to boundary effects, the photoacoustic response is affected by optical effects caused by the presence of the top layer. The interplay of optical effects leads to a complex temporal signal shape that strongly depends on the thickness of the thin film.

了解透明薄膜存在时的光声信号形成过程
应变引起的折射率变化是光声实验中应变检测的主要机制。然而,许多材料中的微弱应变-光学耦合限制了光声学作为成像工具的应用。以前的研究表明,直接沉积一层透明薄膜作为顶层,可以通过弹性边界效应增强信号。在本文中,我们研究了由不同厚度的透明薄膜覆盖的金属中光声信号的形成,并证明除了边界效应外,光声响应还受到顶层存在所导致的光学效应的影响。光学效应的相互作用导致了复杂的时间信号形状,这种形状在很大程度上取决于薄膜的厚度。
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来源期刊
Photoacoustics
Photoacoustics Physics and Astronomy-Atomic and Molecular Physics, and Optics
CiteScore
11.40
自引率
16.50%
发文量
96
审稿时长
53 days
期刊介绍: The open access Photoacoustics journal (PACS) aims to publish original research and review contributions in the field of photoacoustics-optoacoustics-thermoacoustics. This field utilizes acoustical and ultrasonic phenomena excited by electromagnetic radiation for the detection, visualization, and characterization of various materials and biological tissues, including living organisms. Recent advancements in laser technologies, ultrasound detection approaches, inverse theory, and fast reconstruction algorithms have greatly supported the rapid progress in this field. The unique contrast provided by molecular absorption in photoacoustic-optoacoustic-thermoacoustic methods has allowed for addressing unmet biological and medical needs such as pre-clinical research, clinical imaging of vasculature, tissue and disease physiology, drug efficacy, surgery guidance, and therapy monitoring. Applications of this field encompass a wide range of medical imaging and sensing applications, including cancer, vascular diseases, brain neurophysiology, ophthalmology, and diabetes. Moreover, photoacoustics-optoacoustics-thermoacoustics is a multidisciplinary field, with contributions from chemistry and nanotechnology, where novel materials such as biodegradable nanoparticles, organic dyes, targeted agents, theranostic probes, and genetically expressed markers are being actively developed. These advanced materials have significantly improved the signal-to-noise ratio and tissue contrast in photoacoustic methods.
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