Transient kinetics reveal the mechanism of competitive inhibition of the neutral amino acid transporter ASCT2

IF 4.8 2区生物学 Q1 Biochemistry, Genetics and Molecular Biology

Journal of Biological Chemistry Pub Date : 2024-05-01 DOI:10.1016/j.jbc.2024.107382

Yang Dong, Jiali Wang, Christof Grewer

引用次数: 0

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瞬时动力学揭示了中性氨基酸转运体 ASCT2 的竞争性抑制机制

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Biological Chemistry 生物-生化与分子生物学

CiteScore

8.50

自引率

4.20%

发文量

1233

审稿时长

63 days

期刊介绍： The Journal of Biological Chemistry welcomes high-quality science that seeks to elucidate the molecular and cellular basis of biological processes. Papers published in JBC can therefore fall under the umbrellas of not only biological chemistry, chemical biology, or biochemistry, but also allied disciplines such as biophysics, systems biology, RNA biology, immunology, microbiology, neurobiology, epigenetics, computational biology, ’omics, and many more. The outcome of our focus on papers that contribute novel and important mechanistic insights, rather than on a particular topic area, is that JBC is truly a melting pot for scientists across disciplines. In addition, JBC welcomes papers that describe methods that will help scientists push their biochemical inquiries forward and resources that will be of use to the research community.

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