Forced LMX1A expression induces dorsal neural fates and disrupts patterning of human embryonic stem cells into ventral midbrain dopaminergic neurons.

IF 5.9 2区医学 Q1 CELL & TISSUE ENGINEERING

Stem Cell Reports Pub Date : 2024-05-01 DOI:10.1016/j.stemcr.2024.04.010

Pedro Rifes, Janko Kajtez, Josefine Rågård Christiansen, Alrik L. Schörling, Gaurav Singh Rathore, Daniel A Wolf, Andreas Heuer, A. Kirkeby

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强制表达 LMX1A 可诱导背侧神经命运，并破坏人类胚胎干细胞向腹侧中脑多巴胺能神经元的模式化。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Stem Cell Reports CELL & TISSUE ENGINEERING-CELL BIOLOGY

CiteScore

10.50

自引率

1.70%

发文量

200

审稿时长

28 weeks

期刊介绍： Stem Cell Reports publishes high-quality, peer-reviewed research presenting conceptual or practical advances across the breadth of stem cell research and its applications to medicine. Our particular focus on shorter, single-point articles, timely publication, strong editorial decision-making and scientific input by leaders in the field and a "scoop protection" mechanism are reasons to submit your best papers.