{"title":"The importance of optimal medical therapy in patients undergoing lower extremity bypass","authors":"C. Gomez-Sanchez, Michael S. Conte","doi":"10.1097/hco.0000000000001157","DOIUrl":null,"url":null,"abstract":"\n \n The prevalence of peripheral artery disease is growing, with millions of people globally suffering its end-stage manifestation, chronic limb-threatening ischemia (CLTI). Revascularization procedures like lower extremity bypass play a vital role in limb salvage but optimal medical therapy is essential for maximizing the benefit of these procedures and reducing long-term risks of cardiovascular and limb-related events.\n \n \n \n Patients with PAD who undergo lower extremity bypass warrant a comprehensive approach to risk factor modification for both primary and secondary prevention of cardiovascular and limb-related complications. This includes appropriate use of high-intensity statins, smoking cessation, and management of hypertension and diabetes. Additionally, antiplatelet therapy is indicated for all patients with CLTI and additional treatment with low-dose anticoagulation may also be beneficial.\n \n \n \n Optimal medical therapy is essential for optimizing outcomes in patients with PAD undergoing lower extremity bypass.\n","PeriodicalId":55197,"journal":{"name":"Current Opinion in Cardiology","volume":null,"pages":null},"PeriodicalIF":2.0000,"publicationDate":"2024-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Opinion in Cardiology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1097/hco.0000000000001157","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}
引用次数: 0
Abstract
The prevalence of peripheral artery disease is growing, with millions of people globally suffering its end-stage manifestation, chronic limb-threatening ischemia (CLTI). Revascularization procedures like lower extremity bypass play a vital role in limb salvage but optimal medical therapy is essential for maximizing the benefit of these procedures and reducing long-term risks of cardiovascular and limb-related events.
Patients with PAD who undergo lower extremity bypass warrant a comprehensive approach to risk factor modification for both primary and secondary prevention of cardiovascular and limb-related complications. This includes appropriate use of high-intensity statins, smoking cessation, and management of hypertension and diabetes. Additionally, antiplatelet therapy is indicated for all patients with CLTI and additional treatment with low-dose anticoagulation may also be beneficial.
Optimal medical therapy is essential for optimizing outcomes in patients with PAD undergoing lower extremity bypass.
外周动脉疾病的发病率越来越高,全球有数百万人患有这种疾病的终末期表现--慢性肢体缺血(CLTI)。下肢搭桥术等血管重建手术在挽救肢体方面发挥着至关重要的作用,但要最大限度地发挥这些手术的益处,降低心血管和肢体相关事件的长期风险,最佳的医疗治疗至关重要。 接受下肢搭桥术的 PAD 患者需要采取综合方法来改变风险因素,以达到一级和二级预防心血管和肢体相关并发症的目的。这包括适当使用高强度他汀类药物、戒烟、控制高血压和糖尿病。此外,抗血小板治疗适用于所有 CLTI 患者,额外的小剂量抗凝治疗也可能有益。 对于接受下肢搭桥术的 PAD 患者来说,最佳的药物治疗对于优化预后至关重要。
期刊介绍:
Current Opinion in Cardiology is a bimonthly publication offering a unique and wide ranging perspective on the key developments in the field. Each issue features hand-picked review articles from our team of expert editors. With fourteen disciplines published across the year – including arrhythmias, molecular genetics, HDL cholesterol and clinical trials – every issue also contains annotated reference detailing the merits of the most important papers.