{"title":"Bilateral Macular Halo and Full-Thickness Macular Hole Repair in Niemann-Pick Disease Type B","authors":"Ye Li, S. Cherepanoff, A. Fung","doi":"10.1177/24741264241249411","DOIUrl":null,"url":null,"abstract":"Purpose: To report the results of surgery in a patient with Niemann-Pick disease type B, bilateral macular halos, and a full-thickness macular hole (FTMH) in the right eye. Methods: A case was evaluated. Results: A 72-year-old man with Niemann-Pick disease type B presented with an FTMH in the right eye. On examination, the visual acuity (VA) was 20/120 OD and 20/16 OS. Bilateral, symmetric, circular yellow–white deposits encircled the fovea. Optical coherence tomography showed focal parafoveal inner retinal hyperreflectivity bilaterally and an FTMH in the right eye. The patient had a vitrectomy with inner limiting membrane (ILM) peeling; the peeled membrane was unremarkable on cytopathology. Six weeks postoperatively, the MH was closed and the VA had improved to 20/40. Conclusions: Successful MH closure is possible in the presence of macular halos secondary to Niemann-Pick disease type B. Cytopathology of the ILM suggests the ILM is not involved in the pathogenesis of macular halos.","PeriodicalId":17919,"journal":{"name":"Journal of VitreoRetinal Diseases","volume":null,"pages":null},"PeriodicalIF":0.5000,"publicationDate":"2024-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of VitreoRetinal Diseases","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1177/24741264241249411","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"OPHTHALMOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Purpose: To report the results of surgery in a patient with Niemann-Pick disease type B, bilateral macular halos, and a full-thickness macular hole (FTMH) in the right eye. Methods: A case was evaluated. Results: A 72-year-old man with Niemann-Pick disease type B presented with an FTMH in the right eye. On examination, the visual acuity (VA) was 20/120 OD and 20/16 OS. Bilateral, symmetric, circular yellow–white deposits encircled the fovea. Optical coherence tomography showed focal parafoveal inner retinal hyperreflectivity bilaterally and an FTMH in the right eye. The patient had a vitrectomy with inner limiting membrane (ILM) peeling; the peeled membrane was unremarkable on cytopathology. Six weeks postoperatively, the MH was closed and the VA had improved to 20/40. Conclusions: Successful MH closure is possible in the presence of macular halos secondary to Niemann-Pick disease type B. Cytopathology of the ILM suggests the ILM is not involved in the pathogenesis of macular halos.