Intradialytic parenteral nutrition in malnourished patients with chronic kidney disease: a systematic review

Jeovany Martínez-Mesa, Rafaela Cabeda, Veronica Albrecht, Natalia Bassani Schuch, Yudeisy Rodriguez-Hernandez, Nádia Juliana Beraldo Goulart Borges Haubert
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Abstract

Introduction: Malnutrition is a prevalent condition among patients with chronic kidney disease (CKD). Objective: To answer the question of the effect of intradialytic parenteral nutrition (IPN) on malnourished CKD patients undergoing dialysis, a systematic review of clinical trials was performed. Methods: The systematic review was performed according with PRISMA. The review was carried out between September and October 2022. The search strategy included PubMed, Web of Science and LILACS databases. The selection of articles was carried out using the Rayyan platform and to assess the chance of bias, the Rob2 instrument recommended by Cochrane was employed. Results and Conclusions: From 762 article retrieved in the initial strategy only 4 articles were included in the review. In a general view, the use of IPN increased the levels of prealbumin and albumin in the participants. Studies evaluating this topic are sparse. More studies are needed to recommend the use of IPN universally in the context of malnourished patients with CKD.
慢性肾病营养不良患者的椎管内肠外营养:系统综述
导言:营养不良是慢性肾脏病 (CKD) 患者中的一种常见病。研究目的为了回答胰内肠外营养(IPN)对接受透析的营养不良 CKD 患者的影响这一问题,我们对临床试验进行了系统回顾。方法:根据 PRISMA 进行了系统回顾。综述时间为 2022 年 9 月至 10 月。检索策略包括 PubMed、Web of Science 和 LILACS 数据库。使用 Rayyan 平台对文章进行筛选,并使用 Cochrane 推荐的 Rob2 工具评估偏倚几率。结果与结论:在初始策略检索到的 762 篇文章中,只有 4 篇被纳入综述。总体而言,使用 IPN 可提高参与者体内的前白蛋白和白蛋白水平。评估这一主题的研究很少。需要更多的研究来推荐在营养不良的慢性肾脏病患者中普遍使用 IPN。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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