The intersecting effects of race, wealth, and education on AIDS incidence, mortality, and case-fatality rate: a Brazilian cohort study of 28.3 million individuals

Iracema Lua, Laio Magno, Andréa Silva, P. Pinto, João Luiz Bastos, Gabriela S Jesus, Ronaldo Coelho, Maria Ichihara, M. Barreto, Carlos Teles Santos, C. Moucheraud, Pamina Gorbach, James Macinko, Luis Souza, Inês Dourado, D. Rasella
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Abstract

Abstract The relationships between race, education, wealth, their intersections and AIDS morbidity/mortality were analyzed in retrospective cohort of 28.3 million individuals followed for 9 years (2007-2015). Together with several sensitivity analyses, a wide range of interactions on additive and multiplicative scales were estimated. Race, education, and wealth were each strongly associated with all of the AIDS-related outcomes, and the magnitude of the associations increased as intersections were included. A significantly higher risk of illness (aRR: 3.07, 95%CI:2.67-3.53) and death (aRR: 4.96, 95%CI:3.99-6.16) from AIDS was observed at the intersection of Black race, lower educational attainment, and less wealth. A higher case-fatality rate (aRR: 1.62, 95%CI:1.18-2.21) was also seen for the same intersectional group. Historically oppressed groups lying at the intersections of race, education, and wealth, had a considerably higher risk of illness and death from AIDS. AIDS-related interventions will require the implementation of comprehensive intersectoral policies that follow an intersectionality perspective.
种族、财富和教育对艾滋病发病率、死亡率和病死率的交叉影响:对 2 830 万人进行的巴西队列研究
摘要 在对 2830 万人进行了长达 9 年(2007-2015 年)跟踪调查的回顾性队列中,分析了种族、教育、财富及其交叉点与艾滋病发病率/死亡率之间的关系。结合几种敏感性分析,对加法和乘法尺度上的各种交互作用进行了估算。种族、教育程度和财富均与所有艾滋病相关结果密切相关,而且随着交叉分析的加入,相关程度也在增加。在黑人种族、教育程度较低和财富较少的交叉点,观察到因艾滋病而患病(aRR:3.07,95%CI:2.67-3.53)和死亡(aRR:4.96,95%CI:3.99-6.16)的风险明显较高。同一交叉群体的病死率也较高(aRR:1.62,95%CI:1.18-2.21)。处于种族、教育和财富交叉点上的历史受压迫群体患艾滋病和死于艾滋病的风险要高得多。与艾滋病有关的干预措施需要实施全面的跨部门政策,并遵循交叉性观点。
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