Effects of melatonin implants on reproductive performance in sheep: a systematic review and meta-analysis

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-05-13 DOI:10.1071/an23109

E. Uzabacı, Hakan Ustuner

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引用次数: 0

Abstract

Context Sheep are seasonal breeding animals. Different reproduction systems exist to enhance productivity in non-breeding season. One of the methods used in enhancing reproductive performance in sheep breeding is melatonin administration. Aim This study aimed to evaluate the impact of melatonin application on reproductive performance in sheep by meta-analysis according to different factors. Methods To find eligible studies, PubMed and Web of Science databases were searched. Twenty studies published between 1991 and 2021 were included in the meta-analysis. The effect sizes of pregnancy rate, lambing rate and litter size were calculated according to breeds, production characteristics (dairy-meat breeds) and season (breeding–non-breeding). The study estimated the risk ratio for pregnancy and lambing rates, and standardized mean difference for litter size as effect size. Key results The melatonin hormone increases the pregnancy rate by 1.07 times and the lambing rate by 1.36 times. The effect size (risk ratio) of the Rasa Aragonesa breed (1.15) for pregnancy rate and the Merino breed (1.65) for lambing rate was higher than the Sarda breed. Conclusions The positive effect of melatonin was found to be higher in the non-breeding season than in the breeding season for the three reproductive performance traits examined. Implications This study is a comprehensive research study examining the effect of melatonin application in sheep according to different factors.

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褪黑素植入对绵羊繁殖性能的影响：系统综述和荟萃分析

背景绵羊是季节性繁殖动物。在非繁殖季节，有不同的繁殖系统来提高生产力。褪黑素是提高绵羊繁殖性能的方法之一。目的本研究旨在通过荟萃分析，根据不同因素评估褪黑激素的应用对绵羊繁殖性能的影响。方法为了找到符合条件的研究，我们检索了 PubMed 和 Web of Science 数据库。1991年至2021年间发表的20项研究被纳入荟萃分析。根据品种、生产特点（奶牛-肉牛品种）和季节（繁殖-非繁殖）计算了妊娠率、产羔率和产仔数的效应大小。研究估计了妊娠率和产羔率的风险比，并将产仔数的标准化平均差作为效应大小。主要结果褪黑激素可使妊娠率提高 1.07 倍，产羔率提高 1.36 倍。Rasa Aragonesa 品种（1.15）和美利奴品种（1.65）的受孕率和产羔率的效应大小（风险比）均高于 Sarda 品种。结论在所考察的三个繁殖性能性状中，褪黑激素在非繁殖季节的积极作用高于繁殖季节。意义本研究是一项综合研究，根据不同因素考察了褪黑激素在绵羊中的应用效果。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.