Prediction of Adverse Maternal Outcomes in Women with Early-Onset Preeclampsia with Severe Features in Mexico: Validation of the Full-PIERS Model

IF 1.6 Q3 OBSTETRICS & GYNECOLOGY

Obstetrics and Gynecology International Pub Date : 2024-05-15 DOI:10.1155/2024/5520312

Eduardo Ponce Nájera, Marcela Montoya Hinojosa, Rogelio Armando Lozano Galván, Diego González Oropeza

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Abstract

Objective. Validate the full-PIERS model in predicting adverse maternal outcomes in women with early-onset preeclampsia with severe features in our population. Methods. Retrospective cohort study. We applied the full-PIERS model on 130 women with severe early-onset preeclampsia who were treated at a second-level hospital in Nuevo León, México. We validated the full-PIERS model in its ability to discriminate through the AUROC. Results. The full-PIERS model applied to the data obtained in our study had good discrimination, revealing an AUC of 0.718 (95% CI 0.515–0.921; P=0.017). A cut-off of 7.95 was identified as the cut-off point with the best diagnostic performance, with the highest Youden index, presenting a sensitivity of 54.5% and specificity of 99.2% for the development of complications. Conclusion. The full-PIERS model can predict adverse maternal outcomes in women admitted to our hospital with severe early-onset preeclampsia within 48 hours of admission.

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墨西哥早发重度子痫前期孕产妇不良预后预测：全PIERS模型的验证

目的验证全 PIERS 模型在预测我国早发重度子痫前期产妇不良预后方面的有效性。方法：回顾性队列研究。回顾性队列研究。我们对 130 名在墨西哥新莱昂州一家二级医院接受治疗的重度早发型子痫前期妇女应用了全 PIERS 模型。我们通过 AUROC 验证了全 PIERS 模型的分辨能力。结果。应用于本研究数据的全 PIERS 模型具有良好的判别能力，其 AUC 为 0.718（95% CI 0.515-0.921；P=0.017）。7.95分界点被认为是诊断效果最好的分界点，尤登指数最高，对并发症发生的敏感性为54.5%，特异性为99.2%。结论全PIERS模型可以预测我院重度早发型子痫前期产妇在入院48小时内的不良预后。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Obstetrics and Gynecology International OBSTETRICS & GYNECOLOGY-

CiteScore

3.60

自引率

0.00%

发文量

审稿时长

19 weeks

期刊介绍： Obstetrics and Gynecology International is a peer-reviewed, Open Access journal that aims to provide a forum for scientists and clinical professionals working in obstetrics and gynecology. The journal publishes original research articles, review articles, and clinical studies related to obstetrics, maternal-fetal medicine, general gynecology, gynecologic oncology, uro-gynecology, reproductive medicine and infertility, reproductive endocrinology, and sexual medicine.