A small review on recent advances in transdermal drug delivery system

Prakash Raj K, Rajakarthikeyan U, Saranraj L, Sivakumar L, R. Yuvhraj, Buvaneshvaran K
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Abstract

Transdermal drug delivery devices (TDDS), often known as "patches," are dosage forms designed to transfer a therapeutically effective amount of medicine over a patient's skin. Transdermal distribution establishes one of the most important channels for a revolutionary medication delivery method. Transdermal drug delivery has various advantages over traditional delivery methods, such as oral and injection; however, its efficacy is restricted. Transdermal administration traditionally entails pushing a patch containing a medicinal substance onto the skin, which is both convenient and painless, as well as therapeutic first-pass metabolism. It can deliver medications through the skin portal to systemic circulation at a predefined rate while maintaining therapeutically efficacious concentrations for an extended period of time. Around 74% of medications are taken orally, and one has been discovered to be less effective than expected.In this present review article, it covers a brief outline of various recent approaches in their development for transdermal patches.
透皮给药系统最新进展综述
透皮给药装置(TDDS)通常被称为 "贴片",是一种设计用于在患者皮肤上传输有效治疗量药物的剂型。透皮给药为革命性的给药方法建立了最重要的渠道之一。与口服和注射等传统给药方法相比,透皮给药具有各种优势,但其疗效受到限制。透皮给药的传统方法是将含有药物的贴片推入皮肤,既方便又无痛苦,还能进行治疗性的首过代谢。它能以预定的速度将药物通过皮肤入口输送到全身循环,同时在较长的时间内保持治疗有效浓度。约 74% 的药物是口服的,其中一种药物的疗效不如预期。本综述文章简要概述了透皮贴剂的各种最新开发方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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