SUSCEPTIBILITY OF PATHOGENS OF BACTERIAL RESPIRATORY DISEASES OF YOUNG CATTLE AND PIGS TO FLORFENICOL

Abstract

The article presents the results of studying the susceptibility of bacteria, patogens of respiratory diseases of young cattle and pigs, to fluorfenicol. Streptococcus suis, Pasteurella multocida, Bordetella bronchiseptica, Escherichia coli and Staphylococcus aureus were isolated and identified from the nasal exudations of young pigs with bronchopneumonia, and Pasteurella multocida, Streptococcus pneumoniae, Mannheimia haemolytica and Escherichia coli – from the nasal exudations of calves with bronchopneumonia. Among the bacteria isolated from sick piglets, Bordetella bronchiseptica (all isolated bacterial strains were sensitive (88.2%) or moderately sensitive (11.8%)) and Escherichia coli (75% of isolates were sensitive, 25% – moderately sensitive) were the most sensitive to florfenicol. The highest level of susceptibility to florfenicol among bacteria isolated from sick calves was observed in Streptococcus pneumoniae and Mannheimia haemolytica (all strains were sensitive or moderately sensitive). The test results of the susceptibility of bacterial isolates to florfenicol showed a high level of its bacteriostatic activity in relation to both gram-positive and gram-negative microorganisms, the causative agents of bronchopneumonia in young cattle and pigs. The results indicate that florfenicol is an antibiotic of a wide spectrum of antimicrobial action against the causative agents of bacterial bronchopneumonia in cattle and pigs. The high degree of theirs susceptibility to this antibiotic indicates that antimicrobial medicines based on florfenicol are effective means of etiotropic therapy of bacterial respiratory diseases of young cattle and pigs.