Consensus update on the therapeutic approach to patients with neurogenic detrusor overactivity

Actas urologicas espanolas Pub Date : 2024-11-01 DOI:10.1016/j.acuroe.2024.05.013

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Abstract

Introduction and objectives

A Consensus document on the management of patients with neurogenic detrusor overactivity (NDO) was published in 2018. The present document aims to update its recommendations regarding treatment considering the new evidence available, and to contribute to the standardization of the management of this disorder.

Methods

The methodology used was based on a systematic review and the Nominal Group Technique. The clinical coordinator (CC) and the Consensus update group (CUG) defined the questions to be updated and carried out a systematic review to identify the new available evidence. After being evaluated by the expert panel, the relevant recommendations were updated and agreed in a consensus meeting.

Results

A total of 3210 publications were identified and 26 publications that met the inclusion criteria were included. The CUG updated 18 recommendations on the therapeutic approach to NDO. Unanimous consensus was reached on all of them.

Conclusions

Previous recommendations need to be revised due to the availability of new drugs, the increasing evidence on the use of botulinum toxin or neuromodulation procedures, and new surgical options.

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神经源性逼尿肌过度活动患者治疗方法的最新共识。

导言和目标：2018 年发布了一份关于神经源性逼尿肌过度活动（NDO）患者管理的共识文件。本文件旨在根据现有的新证据更新其有关治疗的建议，并促进该疾病管理的标准化：采用的方法基于系统回顾和名义小组技术。临床协调员（CC）和共识更新小组（CUG）确定了需要更新的问题，并进行了系统回顾，以确定现有的新证据。经专家组评估后，更新了相关建议，并在共识会议上达成一致：结果：共确定了 3210 篇出版物，其中 26 篇符合纳入标准。CUG更新了18项关于NDO治疗方法的建议。所有建议均达成一致共识：结论：由于新药物的出现、使用肉毒杆菌毒素或神经调控程序的证据不断增加以及新的手术选择，以前的建议需要进行修订。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Actas urologicas espanolas

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